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> Protein (NX_O95359)
Protein (NX_O95359)
Protein
Gene SymbolTACC2 to neXtProt (NX_O95359)
DescriptionTransforming acidic coiled-coil-containing protein 2
Chromosome10
Location10q26.13 (123748689 ~ 124014060) to Ensembl
Sequene Features : Isoforms 6, Variants 439, PTMs 37 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of microtubule-based process
.astral microtubule organization
.interkinetic nuclear migration
  + 4 more...
.nuclear hormone receptor binding .microtubule cytoskeleton
.microtubule organizing center
.cytoplasm
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
6 439 37
2014-09-19protein level
6 323 37
2014-05-27protein level
6 323 38
2014-02-25protein level
6 320 38
2013-12-09protein level
6 243 38
2013-11-01protein level
6 232 38
2013-09-12protein level
6 232 40
2013-08-17protein level
6 232 40
2013-07-15protein level
6 167 40
2013-06-11protein level
6 167 40
2013-02-12protein level
6 122 161
2012-12-20protein level
6 118 161
2012-10-30protein level
6 139 161
2012-10-07protein level
6 139 40
2012-08-24protein level
6 132 40
2012-07-28protein level
6 132 40
2012-06-08protein level
6 134 40
2012-05-07protein level
6 116 40
2012-04-10protein level
6 116 40
2012-01-13protein level
6 66 40
2011-12-20protein level
6 66 40
2011-11-11protein level
6 66 29
2011-08-23protein level
6 66 29
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O95359-1
0 40 2 112041.7307
NX_O95359-2
0 23 2 64116.0379
NX_O95359-3
0 129 2 300872.2332
NX_O95359-4
0 132 2 309236.5922
NX_O95359-5
1 44 2 119285.2677
NX_O95359-6
0 39 2 108622.8902
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites50
bone69
brain43
connective tissue26
embryonic tissue32
esophagus49
eye28
heart44
intestine181
kidney56
larynx213
liver38
lung8
mammary gland52
mouth362
muscle84
nerve64
ovary68
pancreas60
pharynx98
pituitary gland181
placenta272
prostate94
skin90
stomach271
testis2
thymus25
thyroid171
trachea173
umbilical cord72
uterus56
vascular19
Health State
TissuesTPM*
normal68
breast (mammary gland) tumor42
chondrosarcoma60
colorectal tumor293
esophageal tumor57
gastrointestinal tumor244
germ cell tumor34
head and neck tumor291
liver tumor31
lung tumor58
non-neoplasia41
ovarian tumor26
pancreatic tumor38
primitive neuroectodermal tumor of the CNS7
prostate cancer134
retinoblastoma21
skin tumor7
soft tissue/muscle tissue tumor7
uterine tumor44
Developmental Stage
TissuesTPM*
adult122
embryoid body14
blastocyst48
neonate96
fetus53
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue17.4
adrenal gland13.6
appendix6.5
cerebral cortex15.1
colon25.2
duodenum16.8
esophagus46.8
gallbladder17.8
heart muscle87
kidney13.3
liver5.1
lung27.5
ovary4.5
pancreas7.9
placenta29.2
prostate32.5
salivary gland37.9
skin81.3
small intestine15.3
spleen3
stomach20.1
testis6.6
thyroid gland41.5
urinary bladder17.4
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowLow
breastMedium
bronchusLow
cerebellumLow
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusMedium
fallopian tubeLow
gallbladderMedium
heart muscleLow
kidneyHigh
lateral ventricleMedium
liverMedium
lungMedium
nasopharynxMedium
oral mucosaLow
ovaryLow
pancreasLow
parathyroid glandMedium
placentaHigh
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2Medium
small intestineMedium
smooth muscleMedium
soft tissue 1Medium
soft tissue 2Medium
stomach 1Medium
stomach 2Medium
testisHigh
thyroid glandMedium
tonsilLow
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605302, gene) Transforming, acidic, coiled-coil-containing protein 2; TACC2OMIM


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