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> Protein (NX_O95365)
Protein (NX_O95365)
Protein
Gene SymbolZBTB7A to neXtProt (NX_O95365)
DescriptionZinc finger and BTB domain-containing protein 7A
Chromosome19
Location19p13.3 (4044362 ~ 4066943) to Ensembl
Sequene Features : Isoforms 1, Variants 51, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of transcription, DNA-templated
.cell differentiation
.multicellular organismal development
  + 2 more...
.metal ion binding
.histone acetyltransferase binding
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 51 6
2014-09-19protein level
1 35 6
2014-05-27protein level
1 35 6
2014-02-25protein level
1 35 6
2013-12-09protein level
1 25 6
2013-11-01protein level
1 25 6
2013-09-12protein level
1 25 7
2013-08-17protein level
1 25 7
2013-07-15protein level
1 16 7
2013-06-11protein level
1 16 7
2013-02-12protein level
1 6 10
2012-12-20protein level
1 6 7
2012-10-30protein level
1 8 7
2012-10-07protein level
1 8 7
2012-08-24protein level
1 5 7
2012-07-28protein level
1 5 7
2012-06-08protein level
1 6 7
2012-05-07protein level
1 6 7
2012-04-10protein level
1 6 7
2012-01-13protein level
1 7 7
2011-12-20protein level
1 7 7
2011-11-11protein level
1 7 7
2011-08-23protein level
1 7 7
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O95365-1
20 0 0 61400.5827
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2795384,EBI-1364 KHDRBS1  
  .positive regulation of RNA export from nucleus
.regulation of RNA export from nucleus
.positive regulation of translational initiation
  + 8 more...
.poly(A) RNA binding
.identical protein binding
.poly(U) RNA binding
  + 4 more...
.Grb2-Sos complex
.membrane
.cytoplasm
  + 2 more...
2 EBI-2795384,EBI-10172004 HOMEZ  
  .transcription, DNA-templated
.negative regulation of transcription from RNA polymerase II promoter
.transcription corepressor activity
.sequence-specific DNA binding transcription factor activity
.DNA binding
.cytoplasm
.nucleolus
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland60
ascites50
blood24
bone111
bone marrow20
brain34
cervix20
connective tissue60
ear62
embryonic tissue4
eye119
heart11
intestine86
kidney85
lung65
lymph112
lymph node144
mammary gland33
muscle9
nerve64
pancreas89
parathyroid48
placenta21
prostate131
skin18
spleen56
stomach31
testis6
thymus25
thyroid42
uterus25
vascular19
Health State
TissuesTPM*
normal44
adrenal tumor158
breast (mammary gland) tumor10
cervical tumor28
chondrosarcoma84
colorectal tumor35
gastrointestinal tumor42
germ cell tumor34
glioma130
head and neck tumor7
kidney tumor58
leukemia158
lung tumor58
lymphoma69
non-neoplasia72
pancreatic tumor47
prostate cancer67
retinoblastoma21
skin tumor15
soft tissue/muscle tissue tumor39
uterine tumor11
Developmental Stage
TissuesTPM*
adult55
blastocyst16
fetus28
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue10.1
adrenal gland5.9
appendix7.2
bone marrow6.3
cerebral cortex9.7
colon14.6
duodenum11.7
esophagus10.1
gallbladder6.3
heart muscle4.6
kidney8
liver3.9
lung8.5
lymph node5.8
ovary5.1
pancreas3
placenta5
prostate8.9
salivary gland6.5
skin10.3
small intestine10.2
spleen11.9
stomach15.9
testis2.9
thyroid gland5
urinary bladder6.9
Tissues
TissuesExpression level
adrenal glandMedium
appendixHigh
bone marrowMedium
breastLow
bronchusHigh
cerebellumMedium
cerebral cortexHigh
cervix, uterineHigh
colonHigh
duodenumMedium
endometrium 1Low
endometrium 2Low
epididymisMedium
esophagusHigh
fallopian tubeMedium
gallbladderHigh
heart muscleMedium
hippocampusMedium
kidneyMedium
lateral ventricleMedium
liverLow
lungMedium
lymph nodeLow
nasopharynxHigh
oral mucosaHigh
pancreasMedium
parathyroid glandMedium
placentaMedium
prostateMedium
rectumHigh
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1High
skin 2High
small intestineHigh
smooth muscleMedium
soft tissue 1Medium
soft tissue 2Medium
spleenLow
stomach 1High
stomach 2High
testisMedium
thyroid glandMedium
tonsilHigh
urinary bladderHigh
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605878, gene) Zinc finger- and btb domain-containing protein 7; ZBTB7OMIM


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