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> Protein (NX_O95391)
Protein (NX_O95391)
Protein
Gene SymbolSLU7 to neXtProt (NX_O95391)
DescriptionPre-mRNA-splicing factor SLU7
Chromosome5
Location5q33.3 (159828648 ~ 159848718) to Ensembl
Sequene Features : Isoforms 1, Variants 58, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to heat
.intracellular protein transport
.mRNA splicing, via spliceosome
  + 3 more...
.pre-mRNA 3'-splice site binding
.zinc ion binding
.second spliceosomal transesterification activity
.catalytic step 2 spliceosome
.intracellular membrane-bounded organelle
.small nuclear ribonucleoprotein complex
  + 6 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 58 6
2014-09-19protein level
1 38 6
2014-05-27protein level
1 38 6
2014-02-25protein level
1 38 6
2013-12-09protein level
1 28 6
2013-11-01protein level
1 28 5
2013-09-12protein level
1 28 5
2013-08-17protein level
1 28 5
2013-07-15protein level
1 24 3
2013-06-11protein level
1 24 3
2013-02-12protein level
1 5 3
2012-12-20protein level
1 7 3
2012-10-30protein level
1 8 3
2012-10-07protein level
1 8 3
2012-08-24protein level
1 7 3
2012-07-28protein level
1 6 3
2012-06-08protein level
1 16 3
2012-05-07protein level
1 16 3
2012-04-10protein level
1 16 3
2012-01-13protein level
1 15 3
2011-12-20protein level
1 15 3
2011-11-11protein level
1 15 3
2011-08-23protein level
1 15 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O95391-1
30 0 0 68343.6441
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-750559,EBI-744322 PRPF3  
  .RNA splicing
.mRNA processing
.mRNA splicing, via spliceosome
  + 2 more...
.poly(A) RNA binding
.identical protein binding
.U4/U6 x U5 tri-snRNP complex
.nuclear speck
.Cajal body
  + 4 more...
2 EBI-750559,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
3 EBI-750559,EBI-749111 SF3B2  
  .viral process
.gene expression
.RNA splicing
  + 2 more...
.poly(A) RNA binding .catalytic step 2 spliceosome
.U12-type spliceosomal complex
.spliceosomal complex
.nucleoplasm
4 EBI-750559,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
5 EBI-750559,EBI-538479 PRPF8  
  .gene expression
.RNA splicing
.mRNA processing
  + 3 more...
.pre-mRNA intronic binding
.K63-linked polyubiquitin binding
.poly(A) RNA binding
  + 5 more...
.catalytic step 2 spliceosome
.nuclear speck
.membrane
  + 3 more...
6 EBI-750559,EBI-739624 CEP70  
  .organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .nuclear membrane
.cytosol
.centrosome
  + 2 more...
7 EBI-750559,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
8 EBI-750559,EBI-3390132 WHSC1L1  
  .negative regulation of transcription, DNA-templated
.histone methylation
.transcription, DNA-templated
.chromatin organization
.histone methyltransferase activity (H3-K27 specific)
.histone methyltransferase activity (H3-K4 specific)
.histone-lysine N-methyltransferase activity
.zinc ion binding
.chromosome
.nucleoplasm
.nucleus
9 EBI-750559,EBI-751051 PPIL3  
  .protein folding
.protein peptidyl-prolyl isomerization
.mRNA splicing, via spliceosome
.peptidyl-prolyl cis-trans isomerase activity .catalytic step 2 spliceosome
10 EBI-750559,EBI-741515 THAP1  
  .regulation of mitotic cell cycle
.cell cycle
.regulation of transcription, DNA-templated
  + 2 more...
.sequence-specific DNA binding
.identical protein binding
.zinc ion binding
.PML body
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites50
blood122
bone111
brain74
cervix41
connective tissue80
embryonic tissue37
esophagus49
eye52
heart100
intestine68
kidney42
larynx42
liver73
lung32
lymph158
lymph node144
mammary gland59
mouth75
muscle18
nerve64
ovary39
pancreas51
parathyroid48
pharynx196
pituitary gland181
placenta60
prostate26
skin47
spleen56
testis71
thymus50
thyroid64
tonsil235
trachea57
uterus77
vascular38
Health State
TissuesTPM*
normal60
breast (mammary gland) tumor32
cervical tumor57
chondrosarcoma132
colorectal tumor53
esophageal tumor57
gastrointestinal tumor25
germ cell tumor45
glioma27
head and neck tumor74
kidney tumor43
leukemia84
liver tumor52
lung tumor9
lymphoma124
non-neoplasia72
ovarian tumor26
pancreatic tumor95
primitive neuroectodermal tumor of the CNS55
prostate cancer28
retinoblastoma43
skin tumor63
soft tissue/muscle tissue tumor55
uterine tumor88
Developmental Stage
TissuesTPM*
adult53
embryoid body28
blastocyst16
fetus39
infant170
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue30.3
adrenal gland29.2
appendix28.8
bone marrow51.7
cerebral cortex36.9
colon28.6
duodenum17.3
esophagus24.6
gallbladder18.2
heart muscle24.8
kidney28.8
liver20.8
lung26.6
lymph node27.5
ovary25.7
pancreas10.1
placenta27.1
prostate25.9
salivary gland20.3
skin21.2
small intestine24.8
spleen37.5
stomach32.2
testis42.6
thyroid gland30.3
urinary bladder25.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605974, gene) Slu7 splicing factor, s. cerevisiae, homolog of; SLU7OMIM


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