Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_O95405)
Protein (NX_O95405)
Protein
Gene SymbolZFYVE9 to neXtProt (NX_O95405)
DescriptionZinc finger FYVE domain-containing protein 9
Chromosome1
Location1p32.3 (52608046 ~ 52812358) to Ensembl
Sequene Features : Isoforms 3, Variants 162, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of transforming growth factor beta receptor signaling pathway
.SMAD protein import into nucleus
.SMAD protein complex assembly
  + 3 more...
.metal ion binding
.serine-type peptidase activity
.1-phosphatidylinositol binding
.early endosome membrane
.early endosome
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 162 2
2014-09-19protein level
3 135 2
2014-05-27protein level
3 135 2
2014-02-25protein level
3 131 2
2013-12-09protein level
3 102 2
2013-11-01protein level
3 94 2
2013-09-12protein level
3 94 2
2013-08-17protein level
3 94 2
2013-07-15protein level
3 61 2
2013-06-11protein level
3 61 2
2013-02-12protein level
3 36 0
2012-12-20protein level
3 35 0
2012-10-30protein level
3 40 0
2012-10-07protein level
3 40 0
2012-08-24protein level
3 40 0
2012-07-28protein level
3 40 0
2012-06-08protein level
3 53 0
2012-05-07protein level
3 39 0
2012-04-10protein level
3 39 0
2012-01-13protein level
3 27 0
2011-12-20protein level
3 27 0
2011-11-11protein level
3 27 0
2011-08-23protein level
3 27 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O95405-1
2 55 0 156302.3615
NX_O95405-2
1 55 0 150251.5082
NX_O95405-3
1 32 0 83667.1215
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-296817,EBI-1394177 RHO  
  .retina development in camera-type eye
.regulation of rhodopsin mediated signaling pathway
.protein-chromophore linkage
  + 8 more...
.metal ion binding
.retinal binding
.photoreceptor activity
.G-protein coupled receptor activity
.photoreceptor disc membrane
.photoreceptor inner segment membrane
.ciliary membrane
  + 10 more...
2 EBI-296817,EBI-356283 PPP1CC  
  .cell division
.small molecule metabolic process
.entrainment of circadian clock by photoperiod
  + 10 more...
.protein N-terminus binding
.metal ion binding
.poly(A) RNA binding
  + 4 more...
.PTW/PP1 phosphatase complex
.MLL5-L complex
.protein complex
  + 11 more...
3 EBI-296817,EBI-357253 PPP1CA  
  .positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
.cell division
.branching morphogenesis of an epithelial tube
  + 15 more...
.metal ion binding
.ribonucleoprotein complex binding
.phosphatase activity
.protein serine/threonine phosphatase activity
.PTW/PP1 phosphatase complex
.MLL5-L complex
.extracellular exosome
  + 10 more...
4 EBI-296817,EBI-347161 SMAD3  
  .positive regulation of extracellular matrix assembly
.activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
.extrinsic apoptotic signaling pathway
  + 73 more...
.R-SMAD binding
.co-SMAD binding
.transcription regulatory region DNA binding
  + 21 more...
.SMAD2-SMAD3 protein complex
.SMAD protein complex
.receptor complex
  + 8 more...
5 EBI-296817,EBI-1394295 STX3  
  .positive regulation of protein localization to cell surface
.positive regulation of protein localization to plasma membrane
.long-term synaptic potentiation
  + 7 more...
.arachidonic acid binding
.SNAP receptor activity
.SNARE binding
.extracellular exosome
.neuron projection
.azurophil granule
  + 11 more...
6 EBI-296817,EBI-1040141 SMAD2  
  .positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
.response to cholesterol
.SMAD protein signal transduction
  + 42 more...
.R-SMAD binding
.I-SMAD binding
.co-SMAD binding
  + 15 more...
.SMAD2-SMAD3 protein complex
.SMAD protein complex
.activin responsive factor complex
  + 6 more...
7 EBI-296817,EBI-296693 LRP12  
  .regulation of growth
.signal transduction
.receptor-mediated endocytosis
.endocytosis
.low-density lipoprotein receptor activity .integral component of membrane
.coated pit
.integral component of plasma membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bladder33
blood8
brain20
cervix41
embryonic tissue4
eye9
intestine12
kidney14
liver14
lung11
mammary gland26
mouth15
muscle9
ovary9
pancreas9
pharynx24
prostate36
skin9
stomach20
testis6
thyroid42
umbilical cord145
uterus30
Health State
TissuesTPM*
normal17
breast (mammary gland) tumor42
cervical tumor57
colorectal tumor17
gastrointestinal tumor16
germ cell tumor26
head and neck tumor22
leukemia21
ovarian tumor13
pancreatic tumor19
skin tumor7
uterine tumor11
Developmental Stage
TissuesTPM*
adult22
neonate64
fetus7
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8
adrenal gland8.8
appendix3.4
cerebral cortex17.1
colon7.4
duodenum5.3
esophagus9.8
gallbladder8
heart muscle5.7
kidney10.8
liver4.6
lung9.7
lymph node2.3
ovary15.7
pancreas7.4
placenta5
prostate9.5
salivary gland6.8
skin9
small intestine5.3
spleen3.3
stomach7.1
testis14.8
thyroid gland17.9
urinary bladder12.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603755, gene) Madh-interacting protein; MADHIPOMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center