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> Protein (NX_O95427)
Protein (NX_O95427)
Protein
Gene SymbolPIGN to neXtProt (NX_O95427)
DescriptionGPI ethanolamine phosphate transferase 1
Chromosome18
Location18q21.33 (59710800 ~ 59854351) to Ensembl
Sequene Features : Isoforms 1, Variants 77, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular protein metabolic process
.post-translational protein modification
.preassembly of GPI anchor in ER membrane
.C-terminal protein lipidation
.transferase activity .integral component of membrane
.membrane
.endoplasmic reticulum membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 77 4
2014-09-19protein level
1 66 4
2014-05-27protein level
1 66 4
2014-02-25protein level
1 66 4
2013-12-09protein level
1 47 4
2013-11-01protein level
1 46 4
2013-09-12protein level
1 46 4
2013-08-17protein level
1 46 4
2013-07-15protein level
1 29 3
2013-06-11protein level
1 29 3
2013-02-12protein level
1 14 3
2012-12-20protein level
1 12 3
2012-10-30protein level
1 20 3
2012-10-07protein level
1 20 3
2012-08-24protein level
1 17 3
2012-07-28protein level
1 17 3
2012-06-08protein level
1 17 3
2012-05-07protein level
1 17 3
2012-04-10protein level
1 17 3
2012-01-13protein level
1 14 3
2011-12-20protein level
1 14 3
2011-11-11protein level
1 14 3
2011-08-23transcript level
1 13 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O95427-1
36 0 0 105741.1796
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
ascites25
bladder133
blood8
bone13
bone marrow20
brain28
cervix123
connective tissue73
ear124
embryonic tissue23
eye38
intestine38
liver38
lung11
lymph node11
mammary gland19
mouth120
muscle9
ovary9
pancreas14
pharynx49
placenta17
prostate52
skin9
stomach41
testis96
thymus87
trachea212
uterus21
vascular19
Health State
TissuesTPM*
normal27
breast (mammary gland) tumor10
cervical tumor173
chondrosarcoma24
colorectal tumor17
gastrointestinal tumor42
germ cell tumor41
glioma9
head and neck tumor59
leukemia21
liver tumor20
lung tumor9
non-neoplasia31
ovarian tumor13
pancreatic tumor28
primitive neuroectodermal tumor of the CNS15
prostate cancer77
skin tumor15
soft tissue/muscle tissue tumor55
Developmental Stage
TissuesTPM*
adult20
embryoid body42
blastocyst32
fetus35
infant170
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue9
adrenal gland9.5
appendix11
bone marrow4.3
cerebral cortex8.4
colon18
duodenum11.4
esophagus28.7
gallbladder15.4
heart muscle11.7
kidney8.5
liver7.2
lung9.6
lymph node9.2
ovary10.4
pancreas8.2
placenta13.8
prostate15
salivary gland9.9
skin13.7
small intestine13.8
spleen8.3
stomach17.4
testis16.4
thyroid gland18.7
urinary bladder20.1
Tissues
TissuesExpression level
adrenal glandHigh
appendixMedium
bone marrowMedium
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexHigh
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusHigh
fallopian tubeLow
gallbladderMedium
heart muscleMedium
hippocampusMedium
kidneyMedium
lateral ventricleMedium
liverMedium
lungMedium
lymph nodeLow
nasopharynxMedium
oral mucosaMedium
ovaryLow
pancreasMedium
parathyroid glandMedium
placentaMedium
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1High
skin 2Medium
small intestineMedium
smooth muscleMedium
soft tissue 1High
soft tissue 2Medium
spleenLow
stomach 1High
stomach 2Medium
testisHigh
thyroid glandMedium
tonsilMedium
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*606097, gene) Phosphatidylinositol glycan, class n; PIGNOMIM
2(#614080, phenotype) Multiple congenital anomalies-hypotonia-seizures syndrome 1; MCAHS1OMIM


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