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> Protein (NX_O95671)
Protein (NX_O95671)
Protein
Gene SymbolASMTL to neXtProt (NX_O95671)
DescriptionN-acetylserotonin O-methyltransferase-like protein
ChromosomeX
LocationXp22.33 (1522032 ~ 1572655) to Ensembl
Sequene Features : Isoforms 3, Variants 47, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .O-methyltransferase activity .cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 47 8
2014-09-19protein level
3 24 8
2014-05-27protein level
3 24 8
2014-02-25protein level
3 24 8
2013-12-09protein level
3 32 8
2013-11-01protein level
3 32 8
2013-09-12protein level
3 32 8
2013-08-17protein level
3 32 8
2013-07-15protein level
2 20 8
2013-06-11protein level
2 20 8
2013-02-12protein level
2 11 10
2012-12-20protein level
2 3 10
2012-10-30protein level
2 29 10
2012-10-07protein level
2 29 5
2012-08-24protein level
2 28 5
2012-07-28protein level
2 28 5
2012-06-08protein level
2 28 5
2012-05-07protein level
2 28 5
2012-04-10protein level
2 28 5
2012-01-13protein level
2 5 5
2011-12-20protein level
2 5 5
2011-11-11protein level
2 5 4
2011-08-23protein level
2 5 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O95671-1
0 27 0 68812.7565
NX_O95671-2
1 26 0 67149.831
NX_O95671-3
0 23 0 62403.2315
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-743231,EBI-743494 TDO2  
  .small molecule metabolic process
.cellular nitrogen compound metabolic process
.tryptophan catabolic process to acetyl-CoA
  + 2 more...
.metal ion binding
.heme binding
.oxygen binding
  + 2 more...
.cytosol
2 EBI-743231,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
3 EBI-743231,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
4 EBI-743231,EBI-302345 PNMA1  
  .positive regulation of apoptotic process
.inflammatory response to antigenic stimulus
.N/A .focal adhesion
.cytoplasm
.nucleolus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland182
ascites326
bladder66
blood130
bone69
bone marrow205
brain78
cervix20
connective tissue93
embryonic tissue42
esophagus49
eye71
heart122
intestine56
kidney99
larynx42
liver43
lung53
lymph node11
mammary gland52
mouth45
muscle84
ovary167
pancreas65
pituitary gland121
placenta35
prostate79
salivary gland49
skin28
spleen131
stomach31
testis52
thymus213
thyroid64
tonsil352
trachea57
umbilical cord72
uterus77
vascular77
Health State
TissuesTPM*
normal66
breast (mammary gland) tumor42
chondrosarcoma108
colorectal tumor26
esophageal tumor57
gastrointestinal tumor135
germ cell tumor94
glioma83
head and neck tumor29
kidney tumor116
leukemia158
liver tumor52
lung tumor38
lymphoma69
non-neoplasia93
ovarian tumor144
pancreatic tumor47
primitive neuroectodermal tumor of the CNS141
prostate cancer38
retinoblastoma43
skin tumor15
soft tissue/muscle tissue tumor63
uterine tumor77
Developmental Stage
TissuesTPM*
adult61
embryoid body28
blastocyst81
neonate128
fetus28
infant85
juvenile107
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue12.8
adrenal gland15.5
appendix13.5
bone marrow10.5
cerebral cortex15.6
colon11.2
duodenum8.3
esophagus12.2
gallbladder13.4
heart muscle21.2
kidney19.4
liver14.3
lung11.8
lymph node17.7
ovary22.6
pancreas9.1
placenta10.4
prostate21
salivary gland16.4
skin13.5
small intestine11.9
spleen18.6
stomach11.4
testis10.6
thyroid gland21.5
urinary bladder12.2
Tissues
TissuesExpression level
adrenal glandLow
appendixHigh
bone marrowMedium
breastHigh
bronchusMedium
cerebellumMedium
cerebral cortexHigh
cervix, uterineMedium
colonHigh
duodenumMedium
endometrium 1High
endometrium 2Medium
epididymisHigh
esophagusLow
fallopian tubeHigh
gallbladderMedium
heart muscleMedium
hippocampusMedium
kidneyHigh
lateral ventricleMedium
liverMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
ovaryHigh
pancreasHigh
parathyroid glandMedium
placentaMedium
prostateHigh
rectumHigh
salivary glandMedium
seminal vesicleHigh
skeletal muscleMedium
skin 1High
skin 2Low
small intestineMedium
smooth muscleMedium
soft tissue 1Medium
soft tissue 2Medium
spleenMedium
stomach 1Low
stomach 2Medium
testisHigh
thyroid glandHigh
tonsilHigh
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*300162, gene) Acetylserotonin methyltransferase-like; ASMTLOMIM
2(*400011, gene) Acetylserotonin methyltransferase-like, y-linkedOMIM


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