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> Protein (NX_O95848)
Protein (NX_O95848)
Protein
Gene SymbolNUDT14 to neXtProt (NX_O95848)
DescriptionUridine diphosphate glucose pyrophosphatase
Chromosome14
Location14q32.33 (105639275 ~ 105647660) to Ensembl
Sequene Features : Isoforms 1, Variants 35, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .ADP-ribose diphosphatase activity
.metal ion binding
.UDP-sugar diphosphatase activity
.extracellular exosome
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 35 0
2014-09-19protein level
1 26 0
2014-05-27protein level
1 26 0
2014-02-25protein level
1 26 0
2013-12-09protein level
1 25 0
2013-11-01protein level
1 25 0
2013-09-12protein level
1 25 0
2013-08-17protein level
1 25 0
2013-07-15protein level
1 20 0
2013-06-11protein level
1 20 0
2013-02-12protein level
1 14 0
2012-12-20protein level
1 14 0
2012-10-30protein level
1 14 0
2012-10-07protein level
1 14 0
2012-08-24protein level
1 8 0
2012-07-28protein level
1 8 0
2012-06-08protein level
1 8 0
2012-05-07protein level
1 8 0
2012-04-10protein level
1 8 0
2012-01-13protein level
1 1 0
2011-12-20protein level
1 1 0
2011-11-11protein level
1 1 0
2011-08-23protein level
1 1 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O95848-1
11 0 0 24103.0816
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-536866,EBI-365961 ARAF  
  .negative regulation of apoptotic process
.positive regulation of peptidyl-serine phosphorylation
.regulation of proteasomal ubiquitin-dependent protein catabolic process
  + 2 more...
.metal ion binding
.ATP binding
.receptor signaling protein activity
  + 2 more...
.N/A
2 EBI-536866,EBI-307352 REL  
  .negative regulation of neuron death
.positive regulation of transcription from RNA polymerase II promoter
.innate immune response
  + 10 more...
.sequence-specific DNA binding transcription factor activity
.chromatin binding
.RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II distal enhancer sequence-specific DNA binding
.I-kappaB/NF-kappaB complex
.cytosol
.transcription factor complex
  + 2 more...
3 EBI-536866,EBI-739832 LNX1  
  .protein homooligomerization
.protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.cytoplasm
4 EBI-536866,EBI-597063 ZCCHC10  
  .N/A .zinc ion binding
.nucleic acid binding
.N/A
5 EBI-536866,EBI-741158 WDYHV1  
  .cellular protein modification process .protein-N-terminal glutamine amidohydrolase activity .cytosol
.nucleus
6 EBI-536866,EBI-740897 NIF3L1  
  .negative regulation of nucleic acid-templated transcription
.positive regulation of transcription, DNA-templated
.neuron differentiation
.identical protein binding
.transcription factor binding
.mitochondrion
.cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
brain7
embryonic tissue4
eye9
heart44
intestine8
kidney9
lung65
mammary gland33
muscle18
ovary29
pancreas46
placenta17
prostate5
skin14
stomach10
testis13
tonsil58
trachea19
uterus25
vascular19
Health State
TissuesTPM*
normal17
breast (mammary gland) tumor10
colorectal tumor17
gastrointestinal tumor8
germ cell tumor15
non-neoplasia10
ovarian tumor39
pancreatic tumor9
primitive neuroectodermal tumor of the CNS7
soft tissue/muscle tissue tumor23
Developmental Stage
TissuesTPM*
adult16
embryoid body14
fetus19
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue17.5
adrenal gland11.6
appendix9.1
bone marrow2.4
cerebral cortex14.8
colon13
duodenum17.6
esophagus4.4
gallbladder9.5
heart muscle13.9
kidney22.4
liver5
lung20.8
lymph node8.6
ovary4.8
pancreas15.4
placenta9.8
prostate16.2
salivary gland15
skin16.5
small intestine15.7
spleen11.6
stomach17.4
testis14.1
thyroid gland16.1
urinary bladder7.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*609219, gene) Nucleoside diphosphate-linked moiety x motif 14; NUDT14OMIM


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