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> Protein (NX_O95872)
Protein (NX_O95872)
Protein
Gene SymbolGPANK1 to neXtProt (NX_O95872)
DescriptionG patch domain and ankyrin repeat-containing protein 1
Chromosome6
Location6p21.33 (31629006 ~ 31634060) to Ensembl
Sequene Features : Isoforms 1, Variants 29, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .nucleic acid binding .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 29 2
2014-09-19protein level
1 26 2
2014-05-27protein level
1 26 2
2014-02-25protein level
1 14 2
2013-12-09protein level
1 10 2
2013-11-01protein level
1 10 2
2013-09-12protein level
1 10 2
2013-08-17protein level
1 10 2
2013-07-15protein level
1 10 0
2013-06-11protein level
1 10 0
2013-02-12protein level
1 10 0
2012-12-20protein level
1 10 0
2012-10-30protein level
1 9 0
2012-10-07protein level
1 9 0
2012-08-24transcript level
1 9 0
2012-07-28transcript level
1 9 0
2012-06-08transcript level
1 11 0
2012-05-07transcript level
1 11 0
2012-04-10transcript level
1 11 0
2012-01-13transcript level
1 9 0
2011-12-20transcript level
1 9 0
2011-11-11transcript level
1 9 0
2011-08-23transcript level
1 9 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O95872-1
16 0 0 39289.6149
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-751540,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
2 EBI-751540,EBI-740098 TRIM23  
  .positive regulation of catalytic activity
.protein ubiquitination
.viral process
.small GTPase mediated signal transduction
.identical protein binding
.GDP binding
.ligase activity
  + 5 more...
.extracellular exosome
.lysosomal membrane
.nucleus
.Golgi membrane
3 EBI-751540,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
4 EBI-751540,EBI-717422 TFCP2  
  .regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.sequence-specific DNA binding
.protein C-terminus binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
5 EBI-751540,EBI-10179526 CCDC184  
  .N/A .N/A .cytoplasm
6 EBI-751540,EBI-302345 PNMA1  
  .positive regulation of apoptotic process
.inflammatory response to antigenic stimulus
.N/A .focal adhesion
.cytoplasm
.nucleolus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites25
blood16
bone13
brain5
cervix61
connective tissue6
embryonic tissue4
eye28
heart11
intestine25
kidney4
liver14
lung32
lymph node11
mammary gland26
pancreas4
parathyroid145
pituitary gland60
placenta10
prostate5
skin4
testis20
thymus12
thyroid42
uterus8
Health State
TissuesTPM*
normal12
bladder carcinoma56
breast (mammary gland) tumor10
chondrosarcoma12
colorectal tumor17
gastrointestinal tumor8
germ cell tumor3
glioma46
head and neck tumor14
leukemia21
liver tumor10
lung tumor19
lymphoma13
primitive neuroectodermal tumor of the CNS47
uterine tumor22
Developmental Stage
TissuesTPM*
adult14
embryoid body28
blastocyst65
fetus39
infant212
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8.7
adrenal gland10.8
appendix9.5
bone marrow9.9
cerebral cortex9
colon9.9
duodenum12.9
esophagus9.4
gallbladder10.2
heart muscle15.2
kidney17.3
liver6.4
lung11.1
lymph node14.2
ovary18.6
pancreas6.2
placenta10.6
prostate10.1
salivary gland11
skin9.5
small intestine13.3
spleen12.6
stomach11
testis27.8
thyroid gland15
urinary bladder14.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*142610, gene) G-patch domain- and ankyrin repeats-containing protein 1; GPANK1OMIM


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