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> Protein (NX_O95886)
Protein (NX_O95886)
Protein
Gene SymbolDLGAP3 to neXtProt (NX_O95886)
DescriptionDisks large-associated protein 3
Chromosome1
Location1p34.3 (35331037 ~ 35395186) to Ensembl
Sequene Features : Isoforms 1, Variants 113, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.signaling .beta-amyloid binding .postsynaptic membrane
.cell junction
.postsynaptic density
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 113 2
2014-09-19protein level
1 76 2
2014-05-27protein level
1 76 2
2014-02-25protein level
1 76 2
2013-12-09protein level
1 64 2
2013-11-01protein level
1 61 2
2013-09-12protein level
1 61 9
2013-08-17protein level
1 61 9
2013-07-15protein level
1 37 9
2013-06-11protein level
1 37 9
2013-02-12protein level
1 16 9
2012-12-20protein level
1 15 9
2012-10-30protein level
1 16 9
2012-10-07protein level
1 16 9
2012-08-24protein level
1 6 9
2012-07-28protein level
1 6 9
2012-06-08protein level
1 6 9
2012-05-07protein level
1 6 9
2012-04-10protein level
1 6 9
2012-01-13protein level
1 4 9
2011-12-20protein level
1 4 9
2011-11-11protein level
1 4 9
2011-08-23protein level
1 4 9
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O95886-1
41 0 1 105974.4295
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1752541,EBI-389883 NCK1  
  .negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
.negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
.negative regulation of PERK-mediated unfolded protein response
  + 23 more...
.eukaryotic initiation factor eIF2 binding
.receptor tyrosine kinase binding
.protein binding, bridging
  + 5 more...
.vesicle membrane
.cell-cell junction
.plasma membrane
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain11
embryonic tissue4
eye14
lung2
spleen18
testis22
uterus4
Health State
TissuesTPM*
normal5
germ cell tumor7
glioma27
lung tumor9
non-neoplasia20
primitive neuroectodermal tumor of the CNS7
retinoblastoma21
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult3
embryoid body14
fetus1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
cerebral cortex15
testis3.6
Tissues
TissuesExpression level
cerebellumLow
cerebral cortexMedium
colonLow
heart muscleLow
hippocampusLow
kidneyMedium
lateral ventricleMedium
lungLow
placentaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611413, gene) Discs large-associated protein 3; DLGAP3OMIM


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