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> Protein (NX_O95954)
Protein (NX_O95954)
Protein
Gene SymbolFTCD to neXtProt (NX_O95954)
DescriptionFormimidoyltransferase-cyclodeaminase
Chromosome21
Location21q22.3 (47556176 ~ 47575481) to Ensembl
Sequene Features : Isoforms 4, Variants 119, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.small molecule metabolic process
.tetrahydrofolate interconversion
.cellular nitrogen compound metabolic process
  + 5 more...
.formimidoyltetrahydrofolate cyclodeaminase activity
.glutamate formimidoyltransferase activity
.folic acid binding
.extracellular exosome
.cytosol
.centriole
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 119 0
2014-09-19protein level
4 95 0
2014-05-27protein level
4 89 0
2014-02-25protein level
4 89 0
2013-12-09protein level
4 61 0
2013-11-01protein level
4 60 0
2013-09-12protein level
4 60 1
2013-08-17protein level
4 60 1
2013-07-15protein level
4 47 1
2013-06-11protein level
4 47 1
2013-02-12protein level
4 29 1
2012-12-20protein level
4 28 1
2012-10-30protein level
4 32 1
2012-10-07protein level
4 32 1
2012-08-24protein level
4 29 1
2012-07-28protein level
4 30 1
2012-06-08protein level
4 30 1
2012-05-07protein level
4 30 1
2012-04-10protein level
4 30 1
2012-01-13protein level
4 20 1
2011-12-20protein level
4 20 1
2011-11-11protein level
4 20 1
2011-08-23protein level
4 20 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O95954-1
2 25 0 58889.2199
NX_O95954-2
3 25 0 61237.1889
NX_O95954-3
2 19 0 52731.8023
NX_O95954-4
2 5 0 16492.0955
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10192648,EBI-749265 CCDC155  
  .chromosome localization to nuclear envelope involved in homologous chromosome segregation
.oogenesis
.spermatogenesis
  + 2 more...
.N/A .integral component of membrane
.nuclear outer membrane
.lateral element
.chromosome, telomeric region
2 EBI-10192648,EBI-394607 MED4  
  .positive regulation of transcription, DNA-templated
.androgen receptor signaling pathway
.intracellular steroid hormone receptor signaling pathway
  + 3 more...
.thyroid hormone receptor binding
.vitamin D receptor binding
.ligand-dependent nuclear receptor transcription coactivator activity
  + 3 more...
.mediator complex
.membrane
.nucleoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain3
eye4
kidney104
liver38
pancreas14
placenta7
testis18
uterus4
Health State
TissuesTPM*
normal18
germ cell tumor7
liver tumor41
retinoblastoma21
Developmental Stage
TissuesTPM*
adult6
fetus34
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
duodenum2.5
kidney155.5
liver232.5
ovary1
pancreas1.5
prostate1.9
small intestine2.8
testis22.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#229100, phenotype) Formiminotransferase deficiencyOMIM
2(*606806, gene) Formiminotransferase cyclodeaminase; FTCDOMIM


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