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> Protein (NX_O95990)
Protein (NX_O95990)
Protein
Gene SymbolFAM107A to neXtProt (NX_O95990)
DescriptionProtein FAM107A
Chromosome3
Location3p14.2 (58549844 ~ 58613337) to Ensembl
Sequene Features : Isoforms 4, Variants 30, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of cell growth .N/A .neuron projection
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 30 0
2014-09-19protein level
4 25 0
2014-05-27protein level
4 25 0
2014-02-25protein level
2 23 0
2013-12-09protein level
2 22 0
2013-11-01protein level
2 22 0
2013-09-12protein level
2 22 0
2013-08-17protein level
2 22 0
2013-07-15protein level
2 18 0
2013-06-11protein level
2 18 0
2013-02-12protein level
2 13 0
2012-12-20protein level
2 13 0
2012-10-30protein level
2 13 0
2012-10-07protein level
2 13 0
2012-08-24protein level
2 10 0
2012-07-28protein level
2 10 0
2012-06-08protein level
2 10 0
2012-05-07protein level
2 10 0
2012-04-10protein level
2 10 0
2012-01-13protein level
2 12 0
2011-12-20protein level
2 12 0
2011-11-11protein level
2 12 0
2011-08-23protein level
2 12 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O95990-1
0 7 0 17444.3261
NX_O95990-2
2 4 0 15843.2677
NX_O95990-3
2 7 0 20441.8891
NX_O95990-4
1 7 0 20859.0235
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10192902,EBI-5661036 FSD2  
  .N/A .N/A .N/A
2 EBI-10192902,EBI-741602 TRIM37  
  .aggresome assembly
.protein autoubiquitination
.positive regulation of NF-kappaB transcription factor activity
  + 7 more...
.ubiquitin protein ligase activity
.protein homodimerization activity
.ubiquitin protein ligase binding
  + 5 more...
.perinuclear region of cytoplasm
.aggresome
.cytosol
  + 2 more...
3 EBI-10192902,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
4 EBI-10192902,EBI-726876 RINT1  
  .regulation of signal transduction involved in mitotic G2 DNA damage checkpoint
.regulation of ER to Golgi vesicle-mediated transport
.Golgi vesicle transport
  + 2 more...
.N/A .endoplasmic reticulum membrane
.endoplasmic reticulum
5 EBI-10192902,EBI-739895 USHBP1  
  .N/A .PDZ domain binding .N/A
6 EBI-10192902,EBI-302345 PNMA1  
  .positive regulation of apoptotic process
.inflammatory response to antigenic stimulus
.N/A .focal adhesion
.cytoplasm
.nucleolus
7 EBI-10192902,EBI-10171416 CCDC136  
  .N/A .N/A .integral component of membrane
.mitochondrion
8 EBI-10192902,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
9 EBI-10192902,EBI-10172526 MID2  
  .negative regulation of viral release from host cell
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.phosphoprotein binding
.protein heterodimerization activity
.protein homodimerization activity
  + 3 more...
.extracellular exosome
.microtubule
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
bladder33
bone13
brain21
cervix20
connective tissue13
embryonic tissue14
eye4
heart178
intestine21
kidney18
lung80
mammary gland33
muscle18
nerve64
ovary128
pancreas14
parathyroid48
pharynx73
pituitary gland121
placenta56
prostate63
spleen280
stomach20
testis6
thymus100
thyroid42
trachea19
umbilical cord145
uterus30
vascular19
Health State
TissuesTPM*
normal12
chondrosarcoma36
colorectal tumor17
gastrointestinal tumor8
germ cell tumor30
glioma139
head and neck tumor29
kidney tumor43
non-neoplasia2080
ovarian tumor144
retinoblastoma64
uterine tumor22
Developmental Stage
TissuesTPM*
adult3
fetus1
infant170
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue37.4
adrenal gland6.3
appendix7.3
cerebral cortex232.4
colon15.2
duodenum4.2
esophagus24.3
gallbladder14.8
heart muscle23.4
kidney20.7
liver1.6
lung35.5
lymph node2.7
ovary5.9
pancreas9.6
placenta8.7
prostate23.8
salivary gland30.9
skin4.2
small intestine8.5
spleen24.4
stomach7
testis3.7
thyroid gland17.2
urinary bladder9.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*608295, gene) Family with sequence similarity 107, member a; FAM107AOMIM


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