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> Protein (NX_P00167)
Protein (NX_P00167)
Protein
Gene SymbolCYB5A to neXtProt (NX_P00167)
DescriptionCytochrome b5
Chromosome18
Location18q22.3 (71920530 ~ 71959251) to Ensembl
Sequene Features : Isoforms 3, Variants 18, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.hydrogen ion transmembrane transport
.small molecule metabolic process
.L-ascorbic acid metabolic process
  + 2 more...
.metal ion binding
.heme binding
.enzyme binding
  + 2 more...
.extracellular exosome
.integral component of membrane
.membrane
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 18 5
2014-09-19protein level
3 10 5
2014-05-27protein level
3 10 5
2014-02-25protein level
3 10 5
2013-12-09protein level
3 6 5
2013-11-01protein level
3 6 3
2013-09-12protein level
3 6 2
2013-08-17protein level
3 6 2
2013-07-15protein level
3 4 2
2013-06-11protein level
3 4 2
2013-02-12protein level
3 2 5
2012-12-20protein level
2 2 4
2012-10-30protein level
2 2 4
2012-10-07protein level
2 2 2
2012-08-24protein level
2 2 2
2012-07-28protein level
2 2 2
2012-06-08protein level
2 9 2
2012-05-07protein level
2 9 2
2012-04-10protein level
2 9 2
2012-01-13protein level
2 12 2
2011-12-20protein level
2 12 2
2011-11-11protein level
2 12 2
2011-08-23protein level
2 12 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P00167-1
1 6 0 15320.4643
NX_P00167-2
0 6 0 11261.4591
NX_P00167-3
1 5 0 14159.8376
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bladder66
blood8
bone13
brain24
connective tissue482
embryonic tissue42
eye43
heart67
intestine43
kidney23
liver263
lung56
lymph node11
mammary gland59
mouth60
muscle9
ovary19
pancreas79
parathyroid388
pharynx49
placenta17
prostate311
skin42
stomach52
testis27
thymus50
trachea38
uterus25
vascular19
Health State
TissuesTPM*
normal51
breast (mammary gland) tumor85
chondrosarcoma24
colorectal tumor26
gastrointestinal tumor8
germ cell tumor3
glioma74
head and neck tumor29
kidney tumor14
liver tumor281
lung tumor9
non-neoplasia41
pancreatic tumor19
prostate cancer471
soft tissue/muscle tissue tumor574
uterine tumor22
Developmental Stage
TissuesTPM*
adult116
embryoid body42
blastocyst16
fetus59
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue205.2
adrenal gland67.1
appendix27.3
bone marrow14.5
cerebral cortex19.5
colon87.2
duodenum313.7
esophagus52.2
gallbladder289.1
heart muscle49.2
kidney488.3
liver796.8
lung276.4
lymph node40
ovary134.5
pancreas179.4
placenta65.5
prostate84.6
salivary gland36.6
skin67.8
small intestine290.8
spleen48.8
stomach132.8
testis56.5
thyroid gland28.1
urinary bladder158.7
Tissues
TissuesExpression level
adrenal glandMedium
bone marrowLow
breastLow
bronchusMedium
duodenumHigh
endometrium 1Low
endometrium 2Low
epididymisLow
fallopian tubeLow
gallbladderHigh
kidneyHigh
liverHigh
lungHigh
nasopharynxMedium
pancreasHigh
seminal vesicleMedium
skin 1Low
small intestineHigh
soft tissue 1Low
stomach 1Medium
stomach 2Medium
testisHigh
urinary bladderHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#250790, phenotype) Methemoglobinemia type ivOMIM
2(*613218, gene) Cytochrome b5, type a (microsomal); CYB5AOMIM


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