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> Protein (NX_P00325)
Protein (NX_P00325)
Protein
Gene SymbolADH1B to neXtProt (NX_P00325)
DescriptionAlcohol dehydrogenase 1B
Chromosome4
Location4q23 (100226121 ~ 100242558) to Ensembl
Sequene Features : Isoforms 2, Variants 92, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.small molecule metabolic process
.xenobiotic metabolic process
.ethanol oxidation
.zinc ion binding
.alcohol dehydrogenase activity, zinc-dependent
.cytosol
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 92 2
2014-09-19protein level
2 57 2
2014-05-27protein level
2 57 2
2014-02-25protein level
1 57 2
2013-12-09protein level
1 48 2
2013-11-01protein level
1 44 2
2013-09-12protein level
1 44 2
2013-08-17protein level
1 44 2
2013-07-15protein level
1 35 2
2013-06-11protein level
1 35 2
2013-02-12protein level
1 19 1
2012-12-20protein level
1 17 1
2012-10-30protein level
1 19 1
2012-10-07protein level
1 19 1
2012-08-24protein level
1 13 1
2012-07-28protein level
1 13 1
2012-06-08protein level
1 19 1
2012-05-07protein level
1 19 1
2012-04-10protein level
1 19 1
2012-01-13protein level
1 22 1
2011-12-20protein level
1 23 1
2011-11-11protein level
1 23 1
2011-08-23protein level
1 23 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P00325-1
2 5 13 39828.4828
NX_P00325-2
0 5 13 35389.048
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue4585
adrenal gland789
bladder133
brain24
cervix41
connective tissue73
esophagus446
eye9
heart603
intestine224
kidney42
larynx42
liver1373
lung167
mammary gland509
mouth45
muscle112
nerve708
pancreas37
pharynx220
placenta7
prostate21
skin18
spleen468
stomach219
testis16
thymus125
trachea1487
uterus245
vascular116
Health State
TissuesTPM*
normal189
adrenal tumor79
breast (mammary gland) tumor32
chondrosarcoma60
esophageal tumor173
gastrointestinal tumor42
germ cell tumor11
head and neck tumor7
kidney tumor14
liver tumor822
lung tumor19
non-neoplasia10
pancreatic tumor9
soft tissue/muscle tissue tumor31
uterine tumor11
Developmental Stage
TissuesTPM*
adult105
neonate96
fetus44
juvenile161
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1172.3
adrenal gland150.8
appendix39.8
colon129
duodenum43.1
esophagus106.1
gallbladder176.8
heart muscle110.5
kidney72.4
liver2417.7
lung252.8
lymph node30.3
ovary65.3
pancreas16
placenta5.5
prostate13.3
salivary gland49.2
skin26.5
small intestine72.9
spleen79.8
stomach43.2
testis2.5
thyroid gland12
urinary bladder95.5
Tissues
TissuesExpression level
breastMedium
liverMedium
soft tissue 1Medium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(+103720, gene/phenotype) Alcohol dehydrogenase 1b, class i, beta polypeptide; ADH1BOMIM


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