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> Protein (NX_P00540)
Protein (NX_P00540)
Protein
Gene SymbolMOS to neXtProt (NX_P00540)
DescriptionProto-oncogene serine/threonine-protein kinase mos
Chromosome8
Location8q12.1 (57025501 ~ 57026541) to Ensembl
Sequene Features : Isoforms 1, Variants 64, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of metaphase/anaphase transition of meiotic cell cycle
.establishment of meiotic spindle orientation
.protein autophosphorylation
  + 6 more...
.ATP binding
.MAP kinase kinase kinase activity
.protein serine/threonine kinase activity
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 64 1
2014-09-19protein level
1 46 1
2014-05-27protein level
1 46 1
2014-02-25protein level
1 47 1
2013-12-09protein level
1 43 1
2013-11-01protein level
1 42 1
2013-09-12protein level
1 42 1
2013-08-17protein level
1 42 1
2013-07-15protein level
1 21 1
2013-06-11protein level
1 21 1
2013-02-12protein level
1 8 0
2012-12-20protein level
1 8 0
2012-10-30protein level
1 9 0
2012-10-07protein level
1 9 0
2012-08-24transcript level
1 9 0
2012-07-28transcript level
1 9 0
2012-06-08transcript level
1 9 0
2012-05-07transcript level
1 7 0
2012-04-10transcript level
1 7 0
2012-01-13transcript level
1 6 0
2011-12-20transcript level
1 6 0
2011-11-11transcript level
1 6 0
2011-08-23protein level
1 6 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P00540-1
16 0 0 37795.6005
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1757866,EBI-748961 CCNDBP1  
  .regulation of cell cycle
.cell cycle
.N/A .cytoplasm
.nucleoplasm
.nucleus
2 EBI-1757866,EBI-744302 GFAP  
  .long-term synaptic potentiation
.Bergmann glial cell differentiation
.regulation of neurotransmitter uptake
  + 7 more...
.structural constituent of cytoskeleton .astrocyte end-foot
.cell body
.membrane
  + 3 more...
3 EBI-1757866,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
4 EBI-1757866,EBI-739566 KRT15  
  .activation of mitophagy in response to mitochondrial depolarization
.epidermis development
.scaffold protein binding
.structural constituent of cytoskeleton
.extracellular exosome
.intermediate filament
.nucleus
5 EBI-1757866,EBI-77797 ACTN2  
  .negative regulation of protein localization to cell surface
.positive regulation of potassium ion transmembrane transporter activity
.negative regulation of potassium ion transmembrane transporter activity
  + 13 more...
.titin Z domain binding
.FATZ binding
.protein dimerization activity
  + 8 more...
.extracellular exosome
.dendritic spine
.pseudopodium
  + 9 more...
6 EBI-1757866,EBI-81134 SEC24C  
  .membrane organization
.COPII vesicle coating
.small molecule metabolic process
  + 7 more...
.zinc ion binding .perinuclear region of cytoplasm
.COPII vesicle coat
.ER to Golgi transport vesicle membrane
  + 3 more...
7 EBI-1757866,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
8 EBI-1757866,EBI-359224 TRAF1  
  .regulation of extrinsic apoptotic signaling pathway
.positive regulation of NF-kappaB transcription factor activity
.signal transduction
  + 2 more...
.thioesterase binding
.ubiquitin protein ligase binding
.zinc ion binding
.tumor necrosis factor receptor binding
.cytoplasm
9 EBI-1757866,EBI-739580 CALCOCO2  
  .response to interferon-gamma
.viral process
.protein homodimerization activity .perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.membrane
  + 4 more...
10 EBI-1757866,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
11 EBI-1757866,EBI-739895 USHBP1  
  .N/A .PDZ domain binding .N/A
12 EBI-1757866,EBI-741724 SPERT  
  .N/A .N/A .cytoplasmic membrane-bounded vesicle
13 EBI-1757866,EBI-740680 DYDC1  
  .N/A .N/A .N/A
14 EBI-1757866,EBI-747353 ATRIP  
  .DNA repair
.DNA replication
.DNA damage checkpoint
.K63-linked polyubiquitin binding .nucleoplasm
.nucleus
15 EBI-1757866,EBI-10193358 C17orf59  
  .N/A .N/A .N/A
16 EBI-1757866,EBI-10171416 CCDC136  
  .N/A .N/A .integral component of membrane
.mitochondrion
17 EBI-1757866,EBI-744593 MTMR9  
  .N/A .enzyme regulator activity .cytoplasm
18 EBI-1757866,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
19 EBI-1757866,EBI-2125614 KIFC3  
  .epithelial cell-cell adhesion
.zonula adherens maintenance
.metabolic process
  + 3 more...
.ATPase activity
.ATP binding
.microtubule motor activity
.extracellular exosome
.cytoplasmic vesicle membrane
.zonula adherens
  + 4 more...
20 EBI-1757866,EBI-10172526 MID2  
  .negative regulation of viral release from host cell
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.phosphoprotein binding
.protein heterodimerization activity
.protein homodimerization activity
  + 3 more...
.extracellular exosome
.microtubule
.cytoplasm
21 EBI-1757866,EBI-2212028 SSX2IP  
  .regulation of cell motility
.centrosome organization
.cilium assembly
  + 3 more...
.N/A .protein complex
.ciliary basal body
.centriolar satellite
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
testis6
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*190060, gene) V-mos moloney murine sarcoma viral oncogene homolog; MOSOMIM


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