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> Protein (NX_P00915)
Protein (NX_P00915)
Protein
Gene SymbolCA1 to neXtProt (NX_P00915)
DescriptionCarbonic anhydrase 1
Chromosome8
Location8q21.2 (86239837 ~ 86291243) to Ensembl
Sequene Features : Isoforms 1, Variants 50, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.small molecule metabolic process
.bicarbonate transport
.one-carbon metabolic process
.hydro-lyase activity
.zinc ion binding
.carbonate dehydratase activity
.arylesterase activity
.extracellular exosome
.cytosol
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 50 1
2014-09-19protein level
1 38 1
2014-05-27protein level
1 38 1
2014-02-25protein level
1 37 1
2013-12-09protein level
1 31 1
2013-11-01protein level
1 27 1
2013-09-12protein level
1 27 1
2013-08-17protein level
1 27 1
2013-07-15protein level
1 19 1
2013-06-11protein level
1 19 1
2013-02-12protein level
1 10 1
2012-12-20protein level
1 10 1
2012-10-30protein level
1 12 1
2012-10-07protein level
1 12 1
2012-08-24protein level
1 10 1
2012-07-28protein level
1 10 1
2012-06-08protein level
1 11 1
2012-05-07protein level
1 11 1
2012-04-10protein level
1 11 1
2012-01-13protein level
1 9 1
2011-12-20protein level
1 9 1
2011-11-11protein level
1 9 1
2011-08-23protein level
1 9 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P00915-1
14 0 0 28852.307
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-3912102,EBI-717422 TFCP2  
  .regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.sequence-specific DNA binding
.protein C-terminus binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood9545
bone marrow20
connective tissue67
intestine262
stomach31
Health State
TissuesTPM*
normal354
colorectal tumor62
gastrointestinal tumor25
leukemia31
non-neoplasia10
soft tissue/muscle tissue tumor71
Developmental Stage
TissuesTPM*
adult17
fetus5
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
bone marrow917.4
colon608
kidney1
liver1.2
placenta9.8
skin1
spleen1.1
stomach1.7
Tissues
TissuesExpression level
appendixLow
bone marrowHigh
colonMedium
lungLow
rectumMedium
spleenMedium
stomach 1Low
stomach 2Low
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*114800, gene) Carbonic anhydrase i; CA1OMIM


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