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> Protein (NX_P02675)
Protein (NX_P02675)
Protein
Gene SymbolFGB to neXtProt (NX_P02675)
DescriptionFibrinogen beta chain
Chromosome4
Location4q31.3 (155484108 ~ 155492238) to Ensembl
Sequene Features : Isoforms 1, Variants 83, PTMs 11 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of endothelial cell apoptotic process
.negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
.positive regulation of substrate adhesion-dependent cell spreading
  + 20 more...
.chaperone binding
.structural molecule activity
.blood microparticle
.extracellular exosome
.vesicle
  + 9 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 83 11
2014-09-19protein level
1 68 11
2014-05-27protein level
1 68 11
2014-02-25protein level
1 67 11
2013-12-09protein level
1 61 11
2013-11-01protein level
1 60 11
2013-09-12protein level
1 60 11
2013-08-17protein level
1 60 11
2013-07-15protein level
1 47 11
2013-06-11protein level
1 47 11
2013-02-12protein level
1 26 10
2012-12-20protein level
1 25 10
2012-10-30protein level
1 27 10
2012-10-07protein level
1 27 10
2012-08-24protein level
1 25 10
2012-07-28protein level
1 25 10
2012-06-08protein level
1 28 10
2012-05-07protein level
1 23 10
2012-04-10protein level
1 23 10
2012-01-13protein level
1 22 10
2011-12-20protein level
1 22 10
2011-11-11protein level
1 22 10
2011-08-23protein level
1 22 10
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P02675-1
25 0 0 55892.1038
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
blood695
brain2
cervix20
embryonic tissue14
eye9
heart379
intestine8
kidney80
liver4944
lung23
mammary gland191
muscle94
pancreas9
placenta31
spleen56
testis6
thyroid21
uterus8
Health State
TissuesTPM*
normal305
cervical tumor28
germ cell tumor53
head and neck tumor7
kidney tumor29
leukemia899
liver tumor1582
pancreatic tumor19
uterine tumor22
Developmental Stage
TissuesTPM*
adult249
embryoid body28
fetus745
juvenile161
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
kidney23.5
liver4244.6
lung1.4
placenta1.1
stomach3
Tissues
TissuesExpression level
cerebellumLow
cerebral cortexMedium
colonMedium
endometrium 1Low
liverMedium
lungLow
oral mucosaLow
ovaryLow
placentaLow
skin 1Low
soft tissue 1Low
soft tissue 2Medium
stomach 1Low
testisLow
tonsilLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*134830, gene) Fibrinogen, b beta polypeptide; FGBOMIM
2(#202400, phenotype) Afibrinogenemia, congenitalOMIM


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