Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_P03952)
Protein (NX_P03952)
Protein
Gene SymbolKLKB1 to neXtProt (NX_P03952)
DescriptionPlasma kallikrein
Chromosome4
Location4q35.2 (187130133 ~ 187179625) to Ensembl
Sequene Features : Isoforms 1, Variants 133, PTMs 23 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of fibrinolysis
.fibrinolysis
.plasminogen activation
  + 7 more...
.serine-type endopeptidase activity .extracellular exosome
.plasma membrane
.extracellular space
.extracellular region
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 133 23
2014-09-19protein level
1 98 23
2014-05-27protein level
1 98 23
2014-02-25protein level
1 98 23
2013-12-09protein level
1 81 23
2013-11-01protein level
1 75 23
2013-09-12protein level
1 75 23
2013-08-17protein level
1 75 23
2013-07-15protein level
1 59 23
2013-06-11protein level
1 59 23
2013-02-12protein level
1 39 23
2012-12-20protein level
1 37 23
2012-10-30protein level
1 39 23
2012-10-07protein level
1 39 23
2012-08-24protein level
1 37 23
2012-07-28protein level
1 37 23
2012-06-08protein level
1 38 23
2012-05-07protein level
1 30 23
2012-04-10protein level
1 30 23
2012-01-13protein level
1 20 23
2011-12-20protein level
1 22 23
2011-11-11protein level
1 22 23
2011-08-23protein level
1 22 23
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P03952-1
34 0 1 71322.6443
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain3
connective tissue6
embryonic tissue9
eye14
heart22
intestine4
kidney14
liver126
mammary gland13
pancreas23
parathyroid48
stomach10
thymus12
Health State
TissuesTPM*
normal12
liver tumor124
non-neoplasia10
pancreatic tumor9
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult8
blastocyst32
fetus14
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adrenal gland1.5
duodenum1.5
gallbladder2.1
heart muscle1
kidney2.9
liver121.2
pancreas1
small intestine1.9
testis1.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*229000, gene) Kallikrein b, plasma, 1; KLKB1OMIM
2(#612423, phenotype) Prekallikrein deficiencyOMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center