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> Protein (NX_P03973)
Protein (NX_P03973)
Protein
Gene SymbolSLPI to neXtProt (NX_P03973)
DescriptionAntileukoproteinase
Chromosome20
Location20q13.12 (43880880 ~ 43883205) to Ensembl
Sequene Features : Isoforms 1, Variants 24, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of viral genome replication
.negative regulation of protein binding
.enzyme binding
.serine-type endopeptidase inhibitor activity
.endopeptidase inhibitor activity
.extracellular exosome
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 24 8
2014-09-19protein level
1 15 8
2014-05-27protein level
1 15 8
2014-02-25protein level
1 15 8
2013-12-09protein level
1 12 8
2013-11-01protein level
1 11 8
2013-09-12protein level
1 11 8
2013-08-17protein level
1 11 8
2013-07-15protein level
1 8 8
2013-06-11protein level
1 8 8
2013-02-12protein level
1 4 8
2012-12-20protein level
1 3 8
2012-10-30protein level
1 6 8
2012-10-07protein level
1 6 8
2012-08-24protein level
1 5 8
2012-07-28protein level
1 5 8
2012-06-08protein level
1 5 8
2012-05-07protein level
1 5 8
2012-04-10protein level
1 5 8
2012-01-13protein level
1 0 8
2011-12-20protein level
1 0 8
2011-11-11protein level
1 0 8
2011-08-23protein level
1 0 8
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P03973-1
6 0 0 14315.8691
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-355293,EBI-347996 SGTA  
  .viral process .N/A .cytoplasm
2 EBI-355293,EBI-10175124 FAM9B  
  .spermatid development .N/A .nucleoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
blood32
bone marrow20
brain5
cervix61
connective tissue53
eye90
heart122
intestine47
kidney61
larynx383
liver82
lung59
lymph node22
mammary gland52
mouth30
ovary167
pancreas18
pharynx564
pituitary gland60
placenta49
prostate52
salivary gland98
skin4
stomach52
testis18
trachea57
uterus112
Health State
TissuesTPM*
normal39
breast (mammary gland) tumor10
cervical tumor86
chondrosarcoma12
colorectal tumor53
gastrointestinal tumor33
glioma9
head and neck tumor112
leukemia42
lung tumor29
non-neoplasia41
ovarian tumor210
pancreatic tumor38
skin tumor7
soft tissue/muscle tissue tumor71
uterine tumor266
Developmental Stage
TissuesTPM*
adult54
fetus30
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue33.5
adrenal gland4.8
appendix70.3
bone marrow190.4
cerebral cortex2.7
colon91.1
duodenum5.2
esophagus794.1
gallbladder262.6
heart muscle6.1
kidney41.3
liver105.2
lung680.7
lymph node1.6
ovary2.1
pancreas7.2
placenta6.9
prostate16.2
salivary gland2807.5
skin151.3
small intestine4.8
spleen3.2
stomach139.9
testis11.9
thyroid gland10.9
urinary bladder107.3
Tissues
TissuesExpression level
bronchusMedium
cervix, uterineHigh
fallopian tubeLow
kidneyMedium
nasopharynxHigh
salivary glandLow
seminal vesicleMedium
soft tissue 1Medium
tonsilLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*107285, gene) Secretory leukocyte protease inhibitor; SLPIOMIM


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