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> Protein (NX_P04818)
Protein (NX_P04818)
Protein
Gene SymbolTYMS to neXtProt (NX_P04818)
DescriptionThymidylate synthase
Chromosome18
Location18p11.32 (657604 ~ 673578) to Ensembl
Sequene Features : Isoforms 3, Variants 31, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.intestinal epithelial cell maturation
.nucleobase-containing small molecule metabolic process
.response to folic acid
  + 27 more...
.cofactor binding
.drug binding
.folic acid binding
  + 3 more...
.cytosol
.mitochondrial matrix
.mitochondrial inner membrane
  + 5 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 31 7
2014-09-19protein level
3 25 7
2014-05-27protein level
3 25 7
2014-02-25protein level
3 24 7
2013-12-09protein level
3 20 7
2013-11-01protein level
3 16 5
2013-09-12protein level
3 16 5
2013-08-17protein level
1 16 5
2013-07-15protein level
1 9 1
2013-06-11protein level
1 9 1
2013-02-12protein level
1 6 1
2012-12-20protein level
1 5 1
2012-10-30protein level
1 8 1
2012-10-07protein level
1 8 1
2012-08-24protein level
1 8 1
2012-07-28protein level
1 8 1
2012-06-08protein level
1 9 1
2012-05-07protein level
1 6 1
2012-04-10protein level
1 6 1
2012-01-13protein level
1 4 1
2011-12-20protein level
1 4 1
2011-11-11protein level
1 4 1
2011-08-23protein level
1 4 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P04818-1
1 13 0 35693.0582
NX_P04818-2
1 11 0 31738.1115
NX_P04818-3
1 8 0 26123.317
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland91
ascites125
bladder200
blood73
bone181
bone marrow41
brain33
cervix329
connective tissue40
embryonic tissue126
eye129
heart33
intestine43
kidney71
liver121
lung35
lymph586
lymph node55
mammary gland79
muscle37
ovary49
pancreas32
pharynx49
placenta120
prostate58
salivary gland197
skin61
spleen37
stomach73
testis151
thymus37
thyroid107
uterus142
vascular58
Health State
TissuesTPM*
normal45
adrenal tumor237
bladder carcinoma227
breast (mammary gland) tumor107
cervical tumor376
chondrosarcoma193
colorectal tumor44
gastrointestinal tumor135
germ cell tumor94
glioma37
head and neck tumor67
kidney tumor145
leukemia84
liver tumor93
lung tumor68
lymphoma373
ovarian tumor52
pancreatic tumor66
primitive neuroectodermal tumor of the CNS259
prostate cancer96
retinoblastoma452
skin tumor95
soft tissue/muscle tissue tumor207
uterine tumor88
Developmental Stage
TissuesTPM*
adult62
embryoid body85
blastocyst97
fetus50
infant637
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue6
adrenal gland3.2
appendix37.3
bone marrow92.9
cerebral cortex10.8
colon37.9
duodenum17.2
esophagus15.9
gallbladder7.1
heart muscle2
kidney11.2
liver11.9
lung6.4
lymph node56
ovary2.9
pancreas1.6
placenta35.3
prostate6.7
salivary gland1.7
skin15.2
small intestine22.3
spleen12.2
stomach15.6
testis57.3
thyroid gland4
urinary bladder19.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*188350, gene) Thymidylate synthetase; TYMSOMIM


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