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> Protein (NX_P05120)
Protein (NX_P05120)
Protein
Gene SymbolSERPINB2 to neXtProt (NX_P05120)
DescriptionPlasminogen activator inhibitor 2
Chromosome18
Location18q21.33 (61538926 ~ 61571124) to Ensembl
Sequene Features : Isoforms 1, Variants 99, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of apoptotic process
.fibrinolysis
.negative regulation of endopeptidase activity
.blood coagulation
.serine-type endopeptidase inhibitor activity .plasma membrane
.cytoplasm
.extracellular space
.extracellular region
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 99 5
2014-09-19protein level
1 67 5
2014-05-27protein level
1 67 5
2014-02-25protein level
1 66 5
2013-12-09protein level
1 59 5
2013-11-01protein level
1 56 5
2013-09-12protein level
1 56 5
2013-08-17protein level
1 56 5
2013-07-15protein level
1 42 5
2013-06-11protein level
1 42 5
2013-02-12protein level
1 23 4
2012-12-20protein level
1 23 4
2012-10-30protein level
1 24 4
2012-10-07protein level
1 24 4
2012-08-24protein level
1 22 4
2012-07-28protein level
1 22 4
2012-06-08protein level
1 23 4
2012-05-07protein level
1 17 4
2012-04-10protein level
1 17 4
2012-01-13protein level
1 9 4
2011-12-20protein level
1 9 4
2011-11-11protein level
1 9 4
2011-08-23protein level
1 9 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P05120-1
20 0 0 46566.0172
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
blood899
brain2
cervix41
connective tissue13
embryonic tissue4
esophagus843
heart11
lung116
mammary gland13
mouth30
muscle18
pancreas18
pharynx49
placenta498
skin75
stomach10
uterus12
vascular600
Health State
TissuesTPM*
normal97
breast (mammary gland) tumor21
chondrosarcoma60
esophageal tumor811
gastrointestinal tumor8
glioma9
head and neck tumor22
leukemia95
lung tumor9
non-neoplasia10
Developmental Stage
TissuesTPM*
adult100
blastocyst16
neonate32
fetus16
juvenile125
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue6.5
appendix8.5
bone marrow19.5
esophagus226.6
placenta72.1
salivary gland1.6
skin70.8
urinary bladder1.5
Tissues
TissuesExpression level
adrenal glandMedium
bronchusLow
cerebellumLow
esophagusMedium
gallbladderLow
heart muscleLow
liverLow
lungLow
lymph nodeLow
oral mucosaLow
pancreasHigh
placentaHigh
seminal vesicleLow
skeletal muscleLow
skin 1Low
skin 2Low
soft tissue 1Low
stomach 1Low
stomach 2Low
testisLow
thyroid glandLow
tonsilMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*173390, gene) Serpin peptidase inhibitor, clade b (ovalbumin), member 2; SERPINB2OMIM


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