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> Protein (NX_P05771)
Protein (NX_P05771)
Protein
Gene SymbolPRKCB to neXtProt (NX_P05771)
DescriptionProtein kinase C beta type
Chromosome16
Location16p12.1 (23847322 ~ 24231932) to Ensembl
Sequene Features : Isoforms 2, Variants 156, PTMs 16 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to carbohydrate stimulus
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of B cell receptor signaling pathway
  + 24 more...
.androgen receptor binding
.histone binding
.histone kinase activity (H3-T6 specific)
  + 8 more...
.extracellular exosome
.membrane
.plasma membrane
  + 4 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 156 16
2014-09-19protein level
2 115 16
2014-05-27protein level
2 115 19
2014-02-25protein level
2 115 19
2013-12-09protein level
2 106 19
2013-11-01protein level
2 102 19
2013-09-12protein level
2 102 20
2013-08-17protein level
2 102 20
2013-07-15protein level
2 55 15
2013-06-11protein level
2 55 15
2013-02-12protein level
2 21 24
2012-12-20protein level
2 21 24
2012-10-30protein level
2 23 24
2012-10-07protein level
2 23 15
2012-08-24protein level
2 23 15
2012-07-28protein level
2 23 15
2012-06-08protein level
2 24 15
2012-05-07protein level
2 11 15
2012-04-10protein level
2 11 15
2012-01-13protein level
2 9 15
2011-12-20protein level
2 9 13
2011-11-11protein level
2 9 13
2011-08-23protein level
2 9 13
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P05771-1
2 20 9 76818.8885
NX_P05771-2
2 20 9 76961.9476
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-5774511,EBI-2511516 PHLPP1  
  .phosphatidylinositol-mediated signaling
.neurotrophin TRK receptor signaling pathway
.innate immune response
  + 5 more...
.metal ion binding
.phosphoprotein phosphatase activity
.membrane
.cytosol
.nucleus
2 EBI-706216,EBI-744700 SHCBP1  
  .regulation of neural precursor cell proliferation
.fibroblast growth factor receptor signaling pathway
.N/A .N/A
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
blood122
bone41
bone marrow102
brain112
eye81
heart22
intestine12
kidney9
lung32
lymph67
lymph node479
mammary gland13
placenta7
prostate5
skin9
spleen131
testis25
thymus188
tonsil58
trachea19
uterus25
Health State
TissuesTPM*
normal72
breast (mammary gland) tumor21
germ cell tumor60
glioma27
kidney tumor14
leukemia296
lung tumor68
lymphoma138
non-neoplasia93
primitive neuroectodermal tumor of the CNS23
skin tumor7
uterine tumor11
Developmental Stage
TissuesTPM*
adult39
fetus66
infant42
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.4
adrenal gland2
appendix34
bone marrow27.5
cerebral cortex71.9
colon5.9
duodenum8.6
esophagus8.4
gallbladder8.1
heart muscle2.2
kidney1.9
liver2.1
lung8.8
lymph node62.3
ovary1.1
placenta3.6
prostate6.8
salivary gland1.7
skin7.7
small intestine6
spleen45.5
stomach5.8
testis10.9
thyroid gland8.9
urinary bladder19.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*176970, gene) Protein kinase c, beta-1; PRKCB1OMIM


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