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> Protein (NX_P06702)
Protein (NX_P06702)
Protein
Gene SymbolS100A9 to neXtProt (NX_P06702)
DescriptionProtein S100-A9
Chromosome1
Location1q21.3 (153330330 ~ 153333503) to Ensembl
Sequene Features : Isoforms 1, Variants 20, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of intrinsic apoptotic signaling pathway
.neutrophil aggregation
.regulation of cytoskeleton organization
  + 24 more...
.RAGE receptor binding
.arachidonic acid binding
.Toll-like receptor 4 binding
  + 5 more...
.extracellular exosome
.plasma membrane
.cytoskeleton
  + 4 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 20 4
2014-09-19protein level
1 12 4
2014-05-27protein level
1 12 4
2014-02-25protein level
1 11 4
2013-12-09protein level
1 10 4
2013-11-01protein level
1 9 4
2013-09-12protein level
1 9 4
2013-08-17protein level
1 9 4
2013-07-15protein level
1 7 4
2013-06-11protein level
1 7 4
2013-02-12protein level
1 7 2
2012-12-20protein level
1 6 2
2012-10-30protein level
1 8 2
2012-10-07protein level
1 8 2
2012-08-24protein level
1 8 2
2012-07-28protein level
1 8 2
2012-06-08protein level
1 16 2
2012-05-07protein level
1 14 2
2012-04-10protein level
1 14 2
2012-01-13protein level
1 11 2
2011-12-20protein level
1 11 2
2011-11-11protein level
1 11 2
2011-08-23protein level
1 11 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P06702-1
6 0 0 13233.471
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1055001,EBI-355281 S100A8  
  .positive regulation of intrinsic apoptotic signaling pathway
.neutrophil aggregation
.regulation of cytoskeleton organization
  + 22 more...
.RAGE receptor binding
.arachidonic acid binding
.Toll-like receptor 4 binding
  + 3 more...
.extracellular exosome
.plasma membrane
.cytoskeleton
  + 4 more...
2 EBI-1055001,EBI-714559 ARRB2  
  .positive regulation of DNA biosynthetic process
.negative regulation of release of cytochrome c from mitochondria
.positive regulation of ERK1 and ERK2 cascade
  + 35 more...
.protein complex scaffold
.angiotensin receptor binding
.ubiquitin protein ligase binding
  + 3 more...
.postsynaptic membrane
.dendritic spine
.cytoplasmic vesicle
  + 8 more...
3 EBI-1055001,EBI-743313 ARRB1  
  .positive regulation of histone H4 acetylation
.positive regulation of ERK1 and ERK2 cascade
.membrane organization
  + 24 more...
.transcription regulatory region DNA binding
.cysteine-type endopeptidase inhibitor activity involved in apoptotic process
.angiotensin receptor binding
  + 5 more...
.cytoplasmic vesicle
.pseudopodium
.cytoplasmic vesicle membrane
  + 9 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue310
blood196
bone41
bone marrow1066
brain5
cervix82
embryonic tissue9
esophagus248
eye95
heart44
intestine17
kidney9
larynx937
liver4
lung140
mammary gland13
mouth604
muscle65
pancreas14
pharynx368
placenta7
prostate5
skin14
spleen131
stomach10
thymus12
umbilical cord72
uterus180
vascular58
Health State
TissuesTPM*
normal34
cervical tumor86
chondrosarcoma12
esophageal tumor289
gastrointestinal tumor8
glioma27
head and neck tumor358
kidney tumor29
leukemia232
liver tumor10
lung tumor350
non-neoplasia186
pancreatic tumor19
prostate cancer9
skin tumor15
soft tissue/muscle tissue tumor7
uterine tumor410
Developmental Stage
TissuesTPM*
adult77
embryoid body28
neonate32
fetus8
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue332.1
adrenal gland32.4
appendix903.1
bone marrow4473.7
cerebral cortex11.9
colon37.8
duodenum21.2
esophagus5826.1
gallbladder129.4
heart muscle27.6
kidney9.8
liver90.7
lung176.9
lymph node58.8
ovary3.4
pancreas32.1
placenta279
prostate16.9
salivary gland35.5
skin105.8
small intestine22.6
spleen573.9
stomach19.3
testis13
thyroid gland18.4
urinary bladder624.1
Tissues
TissuesExpression level
bone marrowHigh
cervix, uterineHigh
esophagusHigh
lungMedium
lymph nodeMedium
oral mucosaHigh
prostateLow
skin 1Medium
skin 2High
spleenHigh
tonsilHigh
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*123886, gene) S100 calcium-binding protein a9; S100A9OMIM


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