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> Protein (NX_P07359)
Protein (NX_P07359)
Protein
Gene SymbolGP1BA to neXtProt (NX_P07359)
DescriptionPlatelet glycoprotein Ib alpha chain
Chromosome17
Location17p13.2 (4835592 ~ 4838325) to Ensembl
Sequene Features : Isoforms 1, Variants 71, PTMs 13 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.thrombin receptor signaling pathway
.fibrinolysis
.regulation of blood coagulation
  + 6 more...
.thrombin receptor activity .extracellular exosome
.anchored component of external side of plasma membrane
.membrane
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 71 13
2014-09-19protein level
1 58 13
2014-05-27protein level
1 58 13
2014-02-25protein level
1 54 13
2013-12-09protein level
1 46 13
2013-11-01protein level
1 46 13
2013-09-12protein level
1 46 13
2013-08-17protein level
1 46 13
2013-07-15protein level
1 31 13
2013-06-11protein level
1 31 13
2013-02-12protein level
1 17 16
2012-12-20protein level
1 14 16
2012-10-30protein level
1 17 16
2012-10-07protein level
1 17 16
2012-08-24protein level
1 18 16
2012-07-28protein level
1 19 16
2012-06-08protein level
1 22 14
2012-05-07protein level
1 22 14
2012-04-10protein level
1 22 14
2012-01-13protein level
1 23 14
2011-12-20protein level
1 23 14
2011-11-11protein level
1 23 14
2011-08-23protein level
1 23 14
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P07359-1
26 0 0 71494.9771
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-297082,EBI-981819 VWF  
  .protein homooligomerization
.cell-substrate adhesion
.extracellular matrix organization
  + 9 more...
.chaperone binding
.protein N-terminus binding
.protein homodimerization activity
  + 6 more...
.extracellular exosome
.Weibel-Palade body
.platelet alpha granule lumen
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
embryonic tissue4
lung2
lymph node11
Health State
TissuesTPM*
germ cell tumor7
leukemia10
lymphoma13
Developmental Stage
TissuesTPM*
fetus1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
appendix3.4
bone marrow3
kidney1.1
lymph node13.6
skin1.8
spleen4
Tissues
TissuesExpression level
bone marrowMedium
cerebral cortexMedium
spleenMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#153670, phenotype) Bernard-soulier syndrome, type a2, autosomal dominant; BSSA2OMIM
2(#177820, phenotype) Pseudo-von willebrand disease; VWDPOMIM
3(#231200, phenotype) Bernard-soulier syndrome; BSSOMIM
4(#258660, phenotype) Nonarteritic anterior ischemic optic neuropathy, susceptibility toOMIM
5(*606672, gene) Glycoprotein ib, platelet, alpha polypeptide; GP1BAOMIM


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