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> Protein (NX_P07711)
Protein (NX_P07711)
Protein
Gene SymbolCTSL to neXtProt (NX_P07711)
DescriptionCathepsin L1
Chromosome9
Location9q21.33 (90340434 ~ 90346308) to Ensembl
Sequene Features : Isoforms 1, Variants 17, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to thyroid hormone stimulus
.macrophage apoptotic process
.proteolysis involved in cellular protein catabolic process
  + 9 more...
.serpin family protein binding
.proteoglycan binding
.histone binding
  + 4 more...
.extracellular exosome
.lysosomal lumen
.endolysosome lumen
  + 4 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 17 4
2014-09-19protein level
1 45 4
2014-05-27protein level
1 45 4
2014-02-25protein level
1 45 4
2013-12-09protein level
1 38 4
2013-11-01protein level
1 37 4
2013-09-12protein level
1 37 4
2013-08-17protein level
1 37 4
2013-07-15protein level
1 27 4
2013-06-11protein level
1 27 4
2013-02-12protein level
1 14 4
2012-12-20protein level
1 14 4
2012-10-30protein level
1 14 4
2012-10-07protein level
1 14 4
2012-08-24protein level
1 13 4
2012-07-28protein level
1 13 4
2012-06-08protein level
1 16 4
2012-05-07protein level
1 10 4
2012-04-10protein level
1 10 4
2012-01-13protein level
1 10 4
2011-12-20protein level
1 10 4
2011-11-11protein level
1 10 4
2011-08-23protein level
1 10 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P07711-1
13 0 0 37539.5698
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1220160,EBI-347996 SGTA  
  .viral process .N/A .cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue233
adrenal gland60
ascites75
blood57
bone265
bone marrow20
brain47
cervix144
connective tissue87
embryonic tissue56
eye76
heart89
intestine38
kidney113
liver121
lung158
lymph node11
mammary gland39
muscle197
nerve193
ovary98
pancreas121
parathyroid291
pharynx24
pituitary gland121
placenta635
prostate105
salivary gland49
skin47
spleen37
stomach73
testis48
thymus25
thyroid128
uterus68
vascular96
Health State
TissuesTPM*
normal126
adrenal tumor158
bladder carcinoma113
breast (mammary gland) tumor21
cervical tumor57
chondrosarcoma253
colorectal tumor17
gastrointestinal tumor75
germ cell tumor22
glioma9
head and neck tumor52
kidney tumor29
leukemia21
liver tumor72
lung tumor116
lymphoma13
non-neoplasia82
ovarian tumor105
pancreatic tumor85
primitive neuroectodermal tumor of the CNS55
prostate cancer105
retinoblastoma21
skin tumor71
soft tissue/muscle tissue tumor7
uterine tumor122
Developmental Stage
TissuesTPM*
adult189
embryoid body85
blastocyst32
fetus93
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue203.7
adrenal gland76.9
appendix136.8
bone marrow60.8
cerebral cortex56.5
colon62.9
duodenum39.8
esophagus39.4
gallbladder106.7
heart muscle87.7
kidney165
liver167.6
lung99.8
lymph node104.7
ovary94.3
pancreas31.7
placenta462.5
prostate65.5
salivary gland56.9
skin15.8
small intestine29
spleen84.2
stomach34.4
testis92.4
thyroid gland77.8
urinary bladder128.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*116880, gene) Cathepsin l; CTSLOMIM


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