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> Protein (NX_P08294)
Protein (NX_P08294)
Protein
Gene SymbolSOD3 to neXtProt (NX_P08294)
DescriptionExtracellular superoxide dismutase [Cu-Zn]
Chromosome4
Location4p15.2 (24791534 ~ 24802464) to Ensembl
Sequene Features : Isoforms 1, Variants 7, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.response to copper ion
.removal of superoxide radicals
.response to hypoxia
.response to reactive oxygen species
.zinc ion binding
.heparin binding
.copper ion binding
.superoxide dismutase activity
.extracellular exosome
.extracellular matrix
.trans-Golgi network
  + 5 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 7 5
2014-09-19protein level
1 5 5
2014-05-27protein level
1 5 5
2014-02-25protein level
1 5 5
2013-12-09protein level
1 5 5
2013-11-01protein level
1 5 5
2013-09-12protein level
1 5 5
2013-08-17protein level
1 5 5
2013-07-15protein level
1 5 5
2013-06-11protein level
1 5 5
2013-02-12protein level
1 4 5
2012-12-20protein level
1 4 5
2012-10-30protein level
1 4 5
2012-10-07protein level
1 4 5
2012-08-24protein level
1 4 5
2012-07-28protein level
1 4 5
2012-06-08protein level
1 4 5
2012-05-07protein level
1 4 5
2012-04-10protein level
1 4 5
2012-01-13protein level
1 3 5
2011-12-20protein level
1 3 5
2011-11-11protein level
1 3 5
2011-08-23protein level
1 3 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P08294-1
10 0 0 25834.6006
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10195782,EBI-347996 SGTA  
  .viral process .N/A .cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue388
bone55
brain31
connective tissue342
embryonic tissue18
esophagus99
eye86
heart11
intestine8
kidney28
lung23
mammary gland13
muscle47
nerve386
ovary118
pancreas37
placenta70
prostate10
salivary gland49
skin14
stomach52
testis52
uterus8
vascular38
Health State
TissuesTPM*
normal48
bladder carcinoma170
chondrosarcoma48
colorectal tumor17
gastrointestinal tumor25
glioma18
head and neck tumor7
kidney tumor14
lung tumor9
non-neoplasia341
ovarian tumor13
pancreatic tumor47
prostate cancer9
soft tissue/muscle tissue tumor7
uterine tumor22
Developmental Stage
TissuesTPM*
adult59
embryoid body42
fetus16
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue112.9
adrenal gland10.9
appendix16.8
cerebral cortex3.3
colon31.9
duodenum11.2
esophagus14.7
gallbladder17
heart muscle18.5
kidney34.9
liver2.3
lung29.1
lymph node7.3
ovary12.5
pancreas26.4
placenta29.3
prostate45.8
salivary gland7.8
skin14.1
small intestine8.1
spleen12.8
stomach14.8
testis24
thyroid gland22.8
urinary bladder21.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*185490, gene) Superoxide dismutase 3; SOD3OMIM


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