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> Protein (NX_P09211)
Protein (NX_P09211)
Protein
Gene SymbolGSTP1 to neXtProt (NX_P09211)
DescriptionGlutathione S-transferase P
Chromosome11
Location11q13.2 (67351066 ~ 67354131) to Ensembl
Sequene Features : Isoforms 1, Variants 35, PTMs 11 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of extrinsic apoptotic signaling pathway
.glutathione derivative biosynthetic process
.negative regulation of monocyte chemotactic protein-1 production
  + 27 more...
.nitric oxide binding
.dinitrosyl-iron complex binding
.S-nitrosoglutathione binding
  + 3 more...
.TRAF2-GSTP1 complex
.extracellular exosome
.vesicle
  + 7 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 35 11
2014-09-19protein level
1 27 11
2014-05-27protein level
1 27 11
2014-02-25protein level
1 27 9
2013-12-09protein level
1 17 9
2013-11-01protein level
1 16 8
2013-09-12protein level
1 16 9
2013-08-17protein level
1 16 9
2013-07-15protein level
1 12 6
2013-06-11protein level
1 12 6
2013-02-12protein level
1 8 8
2012-12-20protein level
1 5 8
2012-10-30protein level
1 9 8
2012-10-07protein level
1 9 8
2012-08-24protein level
1 9 8
2012-07-28protein level
1 9 8
2012-06-08protein level
1 12 8
2012-05-07protein level
1 12 6
2012-04-10protein level
1 12 6
2012-01-13protein level
1 16 6
2011-12-20protein level
1 16 6
2011-11-11protein level
1 16 5
2011-08-23protein level
1 16 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P09211-1
10 0 0 23340.9568
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-353467,EBI-2255129 PRDX6  
  .hydrogen peroxide catabolic process
.phospholipid catabolic process
.response to oxidative stress
.response to reactive oxygen species
.peroxiredoxin activity
.ubiquitin protein ligase binding
.antioxidant activity
  + 2 more...
.extracellular exosome
.cytoplasmic membrane-bounded vesicle
.membrane
  + 4 more...
2 EBI-353467,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
3 EBI-353467,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
4 EBI-353467,EBI-355744 TRAF2  
  .positive regulation of extrinsic apoptotic signaling pathway
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
.negative regulation of neuron death
  + 35 more...
.sphingolipid binding
.identical protein binding
.thioesterase binding
  + 10 more...
.IRE1-TRAF2-ASK1 complex
.TRAF2-GSTP1 complex
.membrane raft
  + 7 more...
5 EBI-353467,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
6 EBI-353467,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
7 EBI-353467,EBI-743771 APPBP2  
  .intracellular transport
.metabolic process
.intracellular protein transport
.microtubule motor activity .cytoplasmic vesicle membrane
.microtubule associated complex
.microtubule
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue233
adrenal gland182
ascites1707
bladder133
blood196
bone209
bone marrow82
brain86
cervix61
connective tissue100
embryonic tissue310
esophagus99
eye450
heart189
intestine517
kidney142
larynx170
liver63
lung253
lymph248
lymph node122
mammary gland198
mouth438
muscle178
nerve64
ovary364
pancreas281
parathyroid145
pharynx761
pituitary gland242
placenta392
prostate195
salivary gland296
skin194
spleen56
stomach324
testis45
thymus12
thyroid322
tonsil411
umbilical cord290
uterus301
vascular135
Health State
TissuesTPM*
normal166
bladder carcinoma170
breast (mammary gland) tumor182
cervical tumor28
chondrosarcoma181
colorectal tumor853
esophageal tumor115
gastrointestinal tumor683
germ cell tumor148
glioma251
head and neck tumor597
kidney tumor145
leukemia211
liver tumor62
lung tumor321
lymphoma207
non-neoplasia186
ovarian tumor341
pancreatic tumor485
primitive neuroectodermal tumor of the CNS307
prostate cancer86
retinoblastoma689
skin tumor183
soft tissue/muscle tissue tumor151
uterine tumor421
Developmental Stage
TissuesTPM*
adult301
embryoid body500
blastocyst179
neonate128
fetus140
infant85
juvenile143
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue151.8
adrenal gland179.2
appendix182.7
bone marrow294.6
cerebral cortex88
colon213
duodenum268.9
esophagus914.4
gallbladder352
heart muscle223.9
kidney235.6
liver20.5
lung387.7
lymph node240.7
ovary218.5
pancreas134.7
placenta279.7
prostate151.3
salivary gland135.2
skin335.5
small intestine227.9
spleen184.5
stomach385
testis51.7
thyroid gland414.2
urinary bladder368.1
Tissues
TissuesExpression level
adrenal glandLow
appendixLow
bone marrowLow
breastLow
bronchusHigh
cerebellumLow
cerebral cortexMedium
cervix, uterineMedium
colonLow
duodenumLow
endometrium 1Medium
endometrium 2Medium
epididymisHigh
esophagusLow
fallopian tubeHigh
gallbladderHigh
heart muscleLow
hippocampusLow
kidneyHigh
lateral ventricleLow
liverHigh
lungHigh
lymph nodeLow
nasopharynxHigh
oral mucosaLow
ovaryLow
pancreasHigh
parathyroid glandLow
placentaMedium
prostateMedium
rectumLow
salivary glandLow
seminal vesicleHigh
skin 1Low
skin 2Low
small intestineLow
smooth muscleLow
soft tissue 1Low
soft tissue 2Low
spleenMedium
stomach 1Low
stomach 2Low
testisMedium
thyroid glandHigh
tonsilMedium
urinary bladderHigh
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*134660, gene) Glutathione s-transferase, pi; GSTP1OMIM


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