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> Protein (NX_P09629)
Protein (NX_P09629)
Protein
Gene SymbolHOXB7 to neXtProt (NX_P09629)
DescriptionHomeobox protein Hox-B7
Chromosome17
Location17q21.32 (46684594 ~ 46710934) to Ensembl
Sequene Features : Isoforms 1, Variants 33, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of branching involved in ureteric bud morphogenesis
.embryonic skeletal system morphogenesis
.myeloid cell differentiation
  + 4 more...
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.cytoplasm
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 33 2
2014-09-19protein level
1 1 2
2014-05-27protein level
1 27 2
2014-02-25protein level
1 18 2
2013-12-09protein level
1 6 2
2013-11-01protein level
1 6 2
2013-07-15protein level
1 12 2
2013-06-11protein level
1 12 2
2013-02-12protein level
1 7 2
2012-12-20protein level
1 7 2
2012-10-30protein level
1 8 2
2012-10-07protein level
1 8 2
2012-08-24protein level
1 7 2
2012-07-28protein level
1 7 2
2012-06-08protein level
1 18 2
2012-05-07protein level
1 18 2
2012-04-10protein level
1 18 2
2012-01-13protein level
1 18 2
2011-12-20protein level
1 18 2
2011-11-11protein level
1 18 2
2011-08-23protein level
1 18 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P09629-1
6 0 1 23999.415
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1248457,EBI-357997 XRCC5  
  .establishment of integrated proviral latency
.cellular response to X-ray
.cellular hyperosmotic salinity response
  + 17 more...
.poly(A) RNA binding
.transcription regulatory region DNA binding
.telomeric DNA binding
  + 7 more...
.nonhomologous end joining complex
.Ku70:Ku80 complex
.membrane
  + 7 more...
2 EBI-1248457,EBI-745579 CLK3  
  .protein autophosphorylation
.regulation of RNA splicing
.protein phosphorylation
.poly(A) RNA binding
.ATP binding
.protein tyrosine kinase activity
  + 2 more...
.intermediate filament cytoskeleton
.nuclear speck
.membrane
  + 3 more...
3 EBI-1248457,EBI-352053 PRKDC  
  .signal transduction involved in mitotic G1 DNA damage checkpoint
.rhythmic process
.positive regulation of transcription from RNA polymerase II promoter
  + 27 more...
.poly(A) RNA binding
.transcription factor binding
.ATP binding
  + 4 more...
.nonhomologous end joining complex
.membrane
.DNA-dependent protein kinase-DNA ligase 4 complex
  + 4 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
bone41
brain1
cervix41
connective tissue13
eye4
intestine77
kidney23
liver29
lung17
mammary gland19
muscle56
ovary19
pancreas37
placenta3
prostate15
skin37
stomach31
testis4
uterus21
Health State
TissuesTPM*
normal5
breast (mammary gland) tumor21
cervical tumor57
chondrosarcoma24
colorectal tumor53
gastrointestinal tumor33
germ cell tumor3
glioma18
leukemia31
liver tumor62
lung tumor9
pancreatic tumor76
skin tumor63
soft tissue/muscle tissue tumor47
uterine tumor44
Developmental Stage
TissuesTPM*
adult13
fetus12
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue13.3
adrenal gland9.5
appendix6.1
colon21
duodenum1.3
gallbladder1.6
kidney24.5
lung2.3
lymph node3.1
placenta4.8
prostate1.4
skin2.7
small intestine10.8
spleen2.6
stomach2.4
testis2.6
urinary bladder12.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*142962, gene) Homeobox b7; HOXB7OMIM


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