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> Protein (NX_P0DMM9)
Protein (NX_P0DMM9)
Protein
Gene SymbolSULT1A3 to neXtProt (NX_P0DMM9)
DescriptionSulfotransferase 1A3
Chromosome16
Location16p11.2 (30205754 ~ 30215631) to Ensembl
Sequene Features : Isoforms 3, Variants 4, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.sulfation
.3'-phosphoadenosine 5'-phosphosulfate metabolic process
.small molecule metabolic process
  + 7 more...
.sulfotransferase activity
.aryl sulfotransferase activity
.cytosol
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 4 0
2014-09-19protein level
3 4 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P0DMM9-1
0 0 14 34173.9917
NX_P0DMM9-2
2 0 7 22055.3466
NX_P0DMM9-3
1 0 14 34757.2503
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10196922,EBI-715117 SHMT1  
  .protein homotetramerization
.protein tetramerization
.folic acid metabolic process
  + 9 more...
.protein homodimerization activity
.pyridoxal phosphate binding
.amino acid binding
  + 2 more...
.extracellular exosome
.cytosol
.mitochondrion
  + 3 more...
2 EBI-10196922,EBI-742808 KHDRBS2  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.poly(U) RNA binding
.poly(A) binding
.nucleus
3 EBI-10196922,EBI-740897 NIF3L1  
  .negative regulation of nucleic acid-templated transcription
.positive regulation of transcription, DNA-templated
.neuron differentiation
.identical protein binding
.transcription factor binding
.mitochondrion
.cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
ascites25
bladder33
blood40
bone55
bone marrow61
brain4
cervix103
connective tissue13
embryonic tissue4
esophagus99
eye4
heart55
intestine4
kidney9
liver53
lung17
lymph node33
mammary gland13
mouth15
nerve64
ovary49
pancreas23
parathyroid48
pharynx24
placenta10
prostate5
salivary gland49
skin4
spleen18
stomach20
testis6
thymus12
thyroid21
umbilical cord72
uterus21
vascular19
Health State
TissuesTPM*
normal21
bladder carcinoma113
breast (mammary gland) tumor10
cervical tumor57
chondrosarcoma12
colorectal tumor35
esophageal tumor57
gastrointestinal tumor33
germ cell tumor3
glioma27
head and neck tumor14
kidney tumor14
leukemia52
liver tumor41
lung tumor68
ovarian tumor52
pancreatic tumor47
prostate cancer9
soft tissue/muscle tissue tumor7
uterine tumor33
Developmental Stage
TissuesTPM*
adult29
blastocyst16
neonate32
fetus23
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue13.5
adrenal gland11.6
appendix19.1
bone marrow15
cerebral cortex5.2
colon38
duodenum151.3
esophagus9.1
gallbladder14.7
heart muscle10.3
kidney10.7
liver17.1
lung32.3
lymph node19.9
ovary6.6
pancreas3.2
placenta11
prostate7.4
salivary gland13.4
skin17.8
small intestine107.5
spleen20.6
stomach14.5
testis7
thyroid gland12.1
urinary bladder12.4
Tissues
TissuesExpression level
adrenal glandLow
appendixMedium
cerebral cortexLow
cervix, uterineLow
colonMedium
duodenumMedium
esophagusLow
heart muscleLow
kidneyLow
liverMedium
oral mucosaLow
ovaryLow
pancreasLow
parathyroid glandLow
placentaLow
rectumMedium
salivary glandLow
seminal vesicleLow
skeletal muscleLow
small intestineHigh
stomach 1Medium
stomach 2Medium
testisLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600641, gene) Sulfotransferase family 1a, phenol-preferring, member 3; SULT1A3OMIM


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