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> Protein (NX_P10074)
Protein (NX_P10074)
Protein
Gene SymbolZBTB48 to neXtProt (NX_P10074)
DescriptionZinc finger and BTB domain-containing protein 48
Chromosome1
Location1p36.31 (6640061 ~ 6649340) to Ensembl
Sequene Features : Isoforms 1, Variants 52, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.transcription, DNA-templated .metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.cytoplasm
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 52 1
2014-09-19protein level
1 36 1
2014-05-27protein level
1 36 1
2014-02-25protein level
1 36 1
2013-12-09protein level
1 24 1
2013-11-01protein level
1 21 1
2013-09-12protein level
1 21 1
2013-08-17protein level
1 21 1
2013-07-15protein level
1 13 1
2013-06-11protein level
1 13 1
2013-02-12protein level
1 6 0
2012-12-20protein level
1 6 0
2012-10-30protein level
1 9 0
2012-10-07protein level
1 9 0
2012-08-24protein level
1 9 0
2012-07-28protein level
1 9 0
2012-06-08protein level
1 13 0
2012-05-07protein level
1 9 0
2012-04-10protein level
1 9 0
2012-01-13protein level
1 9 0
2011-12-20protein level
1 9 0
2011-11-11protein level
1 9 0
2011-08-23protein level
1 9 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P10074-1
31 0 0 77004.0049
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-744864,EBI-10172150 KRTAP10-5  
  .N/A .identical protein binding .keratin filament
2 EBI-744864,EBI-742740 ZBTB8A  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
3 EBI-744864,EBI-5666657 GPATCH2L  
  .N/A .N/A .N/A
4 EBI-744864,EBI-744782 NME7  
  .left/right pattern formation
.ciliary receptor clustering involved in smoothened signaling pathway
.intraciliary transport
  + 6 more...
.metal ion binding
.ATP binding
.nucleoside diphosphate kinase activity
.ciliary basal body
.centrosome
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
blood49
bone27
bone marrow61
brain22
cervix20
connective tissue20
embryonic tissue18
eye14
heart22
intestine17
kidney33
liver14
lung32
lymph22
lymph node11
mammary gland19
muscle18
nerve64
ovary29
pancreas9
placenta7
prostate42
salivary gland49
skin4
spleen74
stomach20
testis64
thymus37
thyroid21
tonsil117
trachea19
uterus34
Health State
TissuesTPM*
normal23
breast (mammary gland) tumor32
cervical tumor28
chondrosarcoma24
colorectal tumor26
gastrointestinal tumor25
germ cell tumor15
glioma9
head and neck tumor14
leukemia63
liver tumor10
lung tumor9
lymphoma69
non-neoplasia20
ovarian tumor13
pancreatic tumor9
primitive neuroectodermal tumor of the CNS47
prostate cancer57
soft tissue/muscle tissue tumor39
uterine tumor11
Developmental Stage
TissuesTPM*
adult20
embryoid body14
neonate64
fetus21
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8.5
adrenal gland11.5
appendix15.7
bone marrow12.4
cerebral cortex8.1
colon10.7
duodenum12.7
esophagus12.1
gallbladder14.2
heart muscle8.5
kidney11.7
liver11.6
lung15.9
lymph node17.6
ovary19.9
pancreas7.2
placenta9.9
prostate12
salivary gland13.8
skin17.2
small intestine15.2
spleen23.9
stomach14
testis27.2
thyroid gland16.7
urinary bladder10.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*165270, gene) Gli-kruppel family member hkr3; HKR3OMIM


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