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> Protein (NX_P10301)
Protein (NX_P10301)
Protein
Gene SymbolRRAS to neXtProt (NX_P10301)
DescriptionRas-related protein R-Ras
Chromosome19
Location19q13.33 (50138549 ~ 50143458) to Ensembl
Sequene Features : Isoforms 1, Variants 22, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of ERK1 and ERK2 cascade
.face morphogenesis
.regulation of protein kinase B signaling
  + 7 more...
.protein complex binding
.GDP binding
.GTP binding
.GTPase activity
.extracellular exosome
.focal adhesion
.plasma membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 22 3
2014-09-19protein level
1 16 3
2014-05-27protein level
1 16 3
2014-02-25protein level
1 16 3
2013-12-09protein level
1 12 3
2013-11-01protein level
1 12 3
2013-09-12protein level
1 12 3
2013-08-17protein level
1 12 3
2013-07-15protein level
1 8 3
2013-06-11protein level
1 8 3
2013-02-12protein level
1 5 2
2012-12-20protein level
1 5 2
2012-10-30protein level
1 5 2
2012-10-07protein level
1 5 2
2012-08-24protein level
1 4 2
2012-07-28protein level
1 4 2
2012-06-08protein level
1 4 2
2012-05-07protein level
1 4 2
2012-04-10protein level
1 4 2
2012-01-13protein level
1 3 2
2011-12-20protein level
1 3 2
2011-11-11protein level
1 3 2
2011-08-23protein level
1 3 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P10301-1
11 0 2 23465.823
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-968703,EBI-389883 NCK1  
  .negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
.negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
.negative regulation of PERK-mediated unfolded protein response
  + 23 more...
.eukaryotic initiation factor eIF2 binding
.receptor tyrosine kinase binding
.protein binding, bridging
  + 5 more...
.vesicle membrane
.cell-cell junction
.plasma membrane
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
bladder66
bone111
bone marrow41
brain5
cervix41
connective tissue20
embryonic tissue14
eye23
heart33
intestine38
kidney61
lung50
lymph158
lymph node11
mammary gland26
mouth45
muscle150
ovary29
pancreas84
placenta38
prostate306
skin37
spleen18
stomach31
testis18
thymus12
uterus30
Health State
TissuesTPM*
normal30
bladder carcinoma56
breast (mammary gland) tumor10
chondrosarcoma120
colorectal tumor17
gastrointestinal tumor8
glioma37
head and neck tumor22
kidney tumor87
lung tumor68
lymphoma96
non-neoplasia20
pancreatic tumor161
prostate cancer346
skin tumor7
soft tissue/muscle tissue tumor79
uterine tumor22
Developmental Stage
TissuesTPM*
adult60
embryoid body28
blastocyst16
fetus14
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue88.8
adrenal gland34
appendix35.3
bone marrow2.9
cerebral cortex7.5
colon42.1
duodenum30.4
esophagus46.4
gallbladder45.2
heart muscle112.1
kidney29.2
liver9.2
lung98.6
lymph node31.4
ovary25
pancreas9.7
placenta54
prostate73.5
salivary gland33.9
skin23.4
small intestine37.4
spleen53.1
stomach28.7
testis25.1
thyroid gland25.4
urinary bladder67.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*165090, gene) Related ras viral oncogene homolog; RRASOMIM


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