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> Protein (NX_P10412)
Protein (NX_P10412)
Protein
Gene SymbolHIST1H1E to neXtProt (NX_P10412)
DescriptionHistone H1.4
Chromosome6
Location6p22.2 (26156559 ~ 26157343) to Ensembl
Sequene Features : Isoforms 1, Variants 83, PTMs 12 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.nucleosome positioning
.nucleosome assembly
.poly(A) RNA binding
.chromatin DNA binding
.extracellular exosome
.nuclear heterochromatin
.nucleus
.nucleosome
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 83 12
2014-09-19protein level
1 63 12
2014-05-27protein level
1 63 29
2014-02-25protein level
1 63 27
2013-12-09protein level
1 47 27
2013-11-01protein level
1 47 21
2013-09-12protein level
1 47 22
2013-08-17protein level
1 47 22
2013-07-15protein level
1 25 16
2013-06-11protein level
1 25 16
2013-02-12protein level
1 13 20
2012-12-20protein level
1 13 20
2012-10-30protein level
1 15 20
2012-10-07protein level
1 15 20
2012-08-24protein level
1 12 20
2012-07-28protein level
1 12 20
2012-06-08protein level
1 12 20
2012-05-07protein level
1 8 20
2012-04-10protein level
1 8 20
2012-01-13protein level
1 5 20
2011-12-20protein level
1 5 20
2011-11-11protein level
1 5 18
2011-08-23protein level
1 5 15
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P10412-1
3 0 5 21851.9354
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-358163,EBI-389883 NCK1  
  .negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
.negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
.negative regulation of PERK-mediated unfolded protein response
  + 23 more...
.eukaryotic initiation factor eIF2 binding
.receptor tyrosine kinase binding
.protein binding, bridging
  + 5 more...
.vesicle membrane
.cell-cell junction
.plasma membrane
  + 6 more...
2 EBI-358163,EBI-1265089 L3MBTL1  
  .regulation of cell cycle
.negative regulation of transcription, DNA-templated
.regulation of megakaryocyte differentiation
  + 4 more...
.identical protein binding
.histone binding
.methylated histone binding
  + 6 more...
.plasma membrane
.nucleoplasm
.nucleus
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain3
kidney4
mouth45
Health State
TissuesTPM*
normal2
glioma9
head and neck tumor22
leukemia21
Developmental Stage
TissuesTPM*
adult1
fetus3
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
bone marrow27.7
lymph node2.3
prostate1.6
salivary gland2
spleen1.6
urinary bladder1.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*142220, gene) Histone gene cluster 1, h1 histone family, member e; HIST1H1EOMIM


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