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> Protein (NX_P10911)
Protein (NX_P10911)
Protein
Gene SymbolMCF2 to neXtProt (NX_P10911)
DescriptionProto-oncogene DBL
ChromosomeX
LocationXq27.1 (138663929 ~ 138790386) to Ensembl
Sequene Features : Isoforms 6, Variants 173, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.apoptotic signaling pathway
.regulation of small GTPase mediated signal transduction
.neurotrophin TRK receptor signaling pathway
  + 3 more...
.Rho guanyl-nucleotide exchange factor activity .extracellular exosome
.membrane
.cytoskeleton
.cytosol
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
6 173 0
2014-09-19protein level
6 131 0
2014-05-27protein level
6 130 0
2014-02-25protein level
6 129 0
2013-12-09protein level
6 118 0
2013-11-01protein level
6 107 0
2013-09-12protein level
6 107 0
2013-08-17protein level
6 107 0
2013-07-15protein level
6 68 0
2013-06-11protein level
6 68 0
2013-02-12protein level
5 26 0
2012-12-20protein level
5 25 0
2012-10-30protein level
4 29 0
2012-10-07protein level
4 29 0
2012-08-24protein level
4 17 0
2012-07-28protein level
4 17 0
2012-06-08protein level
4 21 0
2012-05-07protein level
4 21 0
2012-04-10protein level
4 21 0
2012-01-13protein level
4 10 0
2011-12-20protein level
4 10 0
2011-11-11protein level
4 10 0
2011-08-23protein level
4 10 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P10911-1
0 42 0 107604.3468
NX_P10911-2
0 42 0 100344.0777
NX_P10911-3
0 47 0 114302.8154
NX_P10911-4
0 43 0 109366.2333
NX_P10911-5
0 48 0 116064.7019
NX_P10911-6
1 39 0 95878.8562
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1914514,EBI-741141 NME1  
  .cellular response to fatty acid
.cellular response to glucose stimulus
.nucleobase-containing small molecule metabolic process
  + 22 more...
.poly(A) RNA binding
.ribosomal small subunit binding
.identical protein binding
  + 7 more...
.extracellular exosome
.perinuclear region of cytoplasm
.ruffle membrane
  + 7 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
brain14
connective tissue13
eye9
pancreas14
pituitary gland60
skin14
testis48
Health State
TissuesTPM*
normal11
germ cell tumor7
soft tissue/muscle tissue tumor15
Developmental Stage
TissuesTPM*
adult3
fetus7
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adrenal gland32.1
cerebral cortex5.2
kidney1.3
ovary10.4
testis20.7
thyroid gland1.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*311030, gene) Mcf.2 cell line-derived transforming sequence; MCF2OMIM


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