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> Protein (NX_P11836)
Protein (NX_P11836)
Protein
Gene SymbolMS4A1 to neXtProt (NX_P11836)
DescriptionB-lymphocyte antigen CD20
Chromosome11
Location11q12.2 (60223225 ~ 60238233) to Ensembl
Sequene Features : Isoforms 2, Variants 52, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.B cell proliferation
.humoral immune response
.MHC class II protein complex binding .extracellular exosome
.external side of plasma membrane
.integral component of plasma membrane
.extracellular space
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 52 3
2014-09-19protein level
1 40 3
2014-05-27protein level
1 40 3
2014-02-25protein level
1 38 3
2013-12-09protein level
1 31 3
2013-11-01protein level
1 31 3
2013-09-12protein level
1 31 3
2013-08-17protein level
1 31 3
2013-07-15protein level
1 23 3
2013-06-11protein level
1 23 3
2013-02-12protein level
1 9 5
2012-12-20protein level
1 8 3
2012-10-30protein level
1 13 3
2012-10-07protein level
1 13 3
2012-08-24protein level
1 12 3
2012-07-28protein level
1 12 3
2012-06-08protein level
1 20 3
2012-05-07protein level
1 13 3
2012-04-10protein level
1 13 3
2012-01-13protein level
1 8 3
2011-12-20protein level
1 8 3
2011-11-11protein level
1 8 3
2011-08-23protein level
1 8 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P11836-1
6 5 0 33055.6518
NX_P11836-2
1 5 0 14572.1253
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2808234,EBI-749265 CCDC155  
  .chromosome localization to nuclear envelope involved in homologous chromosome segregation
.oogenesis
.spermatogenesis
  + 2 more...
.N/A .integral component of membrane
.nuclear outer membrane
.lateral element
.chromosome, telomeric region
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood368
connective tissue40
intestine4
kidney4
lung8
lymph112
lymph node701
mammary gland19
pancreas32
parathyroid48
pharynx343
prostate5
skin4
spleen1030
stomach10
testis4
thymus351
tonsil58
trachea19
vascular19
Health State
TissuesTPM*
normal44
breast (mammary gland) tumor32
chondrosarcoma24
leukemia254
lung tumor9
lymphoma318
non-neoplasia41
pancreatic tumor47
skin tumor7
Developmental Stage
TissuesTPM*
adult5
fetus8
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.7
appendix203.2
bone marrow22
colon11.4
duodenum2.1
esophagus2.9
gallbladder15.3
heart muscle2
liver3.9
lung6
lymph node583.2
prostate4.5
salivary gland8.9
small intestine10.1
spleen325
stomach31.8
testis2.2
urinary bladder40.4
Tissues
TissuesExpression level
appendixHigh
bone marrowMedium
lungLow
lymph nodeHigh
spleenHigh
tonsilHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*112210, gene) Membrane-spanning 4 domains, subfamily a, member 1; MS4A1OMIM
2(#613495, phenotype) Immunodeficiency, common variable, 5; CVID5OMIM


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