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> Protein (NX_P11926)
Protein (NX_P11926)
Protein
Gene SymbolODC1 to neXtProt (NX_P11926)
DescriptionOrnithine decarboxylase
Chromosome2
Location2p25.1 (10580094 ~ 10588630) to Ensembl
Sequene Features : Isoforms 1, Variants 44, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.small molecule metabolic process
.regulation of protein catabolic process
.cellular nitrogen compound metabolic process
  + 6 more...
.protein homodimerization activity
.ornithine decarboxylase activity
.cytosol
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 44 3
2014-09-19protein level
1 32 3
2014-05-27protein level
1 32 3
2014-02-25protein level
1 31 3
2013-12-09protein level
1 25 3
2013-11-01protein level
1 25 3
2013-09-12protein level
1 25 3
2013-08-17protein level
1 25 3
2013-07-15protein level
1 20 3
2013-06-11protein level
1 20 3
2013-02-12protein level
1 14 3
2012-12-20protein level
1 15 3
2012-10-30protein level
1 18 3
2012-10-07protein level
1 18 3
2012-08-24protein level
1 12 3
2012-07-28protein level
1 12 3
2012-06-08protein level
1 13 3
2012-05-07protein level
1 12 3
2012-04-10protein level
1 12 3
2012-01-13protein level
1 12 3
2011-12-20protein level
1 12 3
2011-11-11protein level
1 12 3
2011-08-23protein level
1 12 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P11926-1
17 0 0 51115.1115
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1044287,EBI-399080 KAT5  
  .positive regulation of protein acetylation
.cellular response to estradiol stimulus
.positive regulation of transcription from RNA polymerase II promoter
  + 14 more...
.repressing transcription factor binding
.androgen receptor binding
.metal ion binding
  + 2 more...
.perinuclear region of cytoplasm
.NuA4 histone acetyltransferase complex
.Piccolo NuA4 histone acetyltransferase complex
  + 6 more...
2 EBI-1044287,EBI-739467 GORASP2  
  .organelle organization
.mitotic cell cycle
.N/A .membrane
.Golgi apparatus
.Golgi membrane
3 EBI-1044287,EBI-10281601 OAZ3  
  .negative regulation of polyamine transmembrane transport
.positive regulation of protein catabolic process
.small molecule metabolic process
  + 6 more...
.putrescine transmembrane transporter activity
.ornithine decarboxylase inhibitor activity
.blood microparticle
.sperm flagellum
.cytosol
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue233
adrenal gland91
ascites351
bladder100
blood130
bone97
bone marrow82
brain95
cervix433
connective tissue167
embryonic tissue239
esophagus297
eye258
heart44
intestine237
kidney85
larynx468
liver146
lung229
lymph744
lymph node100
mammary gland59
mouth105
muscle197
nerve321
ovary206
pancreas201
parathyroid145
pharynx49
pituitary gland121
placenta229
prostate348
salivary gland148
skin251
spleen18
stomach313
testis236
thymus25
thyroid386
tonsil587
trachea19
umbilical cord72
uterus172
vascular174
Health State
TissuesTPM*
normal103
adrenal tumor158
breast (mammary gland) tumor64
cervical tumor608
chondrosarcoma181
colorectal tumor382
esophageal tumor347
gastrointestinal tumor312
germ cell tumor338
glioma167
head and neck tumor254
kidney tumor101
leukemia137
liver tumor249
lung tumor467
lymphoma526
non-neoplasia41
ovarian tumor144
pancreatic tumor238
primitive neuroectodermal tumor of the CNS330
prostate cancer577
retinoblastoma732
skin tumor406
soft tissue/muscle tissue tumor351
uterine tumor255
Developmental Stage
TissuesTPM*
adult179
embryoid body285
blastocyst195
neonate32
fetus93
infant212
juvenile179
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue40
adrenal gland16.3
appendix65.4
bone marrow110.8
cerebral cortex31.1
colon68.9
duodenum27.6
esophagus29.1
gallbladder44.6
heart muscle42.6
kidney69
liver27
lung45.7
lymph node98.1
ovary50.3
pancreas28.2
placenta17.1
prostate77.8
salivary gland18.7
skin7.1
small intestine32.4
spleen41.2
stomach37
testis123.9
thyroid gland51.5
urinary bladder64
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*165640, gene) Ornithine decarboxylase 1; ODC1OMIM


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