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> Protein (NX_P12235)
Protein (NX_P12235)
Protein
Gene SymbolSLC25A4 to neXtProt (NX_P12235)
DescriptionADP/ATP translocase 1
Chromosome4
Location4q35.1 (186064395 ~ 186071536) to Ensembl
Sequene Features : Isoforms 1, Variants 33, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of necroptotic process
.regulation of insulin secretion
.small molecule metabolic process
  + 7 more...
.adenine transmembrane transporter activity .integral component of plasma membrane
.mitochondrial inner membrane
.mitochondrion
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 33 7
2014-09-19protein level
1 26 7
2014-05-27protein level
1 26 12
2014-02-25protein level
1 26 6
2013-12-09protein level
1 23 6
2013-11-01protein level
1 23 2
2013-09-12protein level
1 23 2
2013-08-17protein level
1 23 2
2013-07-15protein level
1 19 2
2013-06-11protein level
1 19 2
2013-02-12protein level
1 10 2
2012-12-20protein level
1 10 2
2012-10-30protein level
1 11 2
2012-10-07protein level
1 11 10
2012-08-24protein level
1 11 10
2012-07-28protein level
1 11 10
2012-06-08protein level
1 14 10
2012-05-07protein level
1 13 10
2012-04-10protein level
1 13 10
2012-01-13protein level
1 13 10
2011-12-20protein level
1 13 10
2011-11-11protein level
1 13 10
2011-08-23protein level
1 13 7
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P12235-1
6 0 11 33043.1219
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-359074,EBI-5323863 LRRK2  
  .negative regulation of peroxidase activity
.regulation of synaptic vesicle exocytosis
.regulation of branching morphogenesis of a nerve
  + 64 more...
.protein kinase A binding
.ion channel binding
.protein homodimerization activity
  + 18 more...
.extracellular exosome
.membrane raft
.perikaryon
  + 25 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland91
blood16
bone41
bone marrow20
brain115
cervix103
embryonic tissue61
eye100
heart279
intestine51
kidney56
larynx127
liver4
lung41
lymph67
mammary gland39
muscle150
nerve193
pancreas84
parathyroid339
pituitary gland242
placenta49
prostate84
skin23
stomach104
testis121
thymus37
thyroid85
uterus30
vascular58
Health State
TissuesTPM*
normal60
breast (mammary gland) tumor53
cervical tumor28
colorectal tumor35
gastrointestinal tumor42
germ cell tumor18
glioma55
head and neck tumor67
kidney tumor58
leukemia21
liver tumor10
lung tumor19
lymphoma69
non-neoplasia41
pancreatic tumor38
primitive neuroectodermal tumor of the CNS7
prostate cancer86
retinoblastoma129
skin tumor15
soft tissue/muscle tissue tumor15
uterine tumor33
Developmental Stage
TissuesTPM*
adult66
embryoid body57
blastocyst48
fetus50
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue17.8
adrenal gland27.2
appendix9.8
bone marrow1.1
cerebral cortex48.1
colon23.8
duodenum20
esophagus37.1
gallbladder15.2
heart muscle583.3
kidney57.4
liver19.6
lung18.6
lymph node6
ovary13
pancreas10.4
placenta10.1
prostate56.4
salivary gland23.5
skin4.8
small intestine20.3
spleen7.5
stomach30.4
testis26.4
thyroid gland22.3
urinary bladder17.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*103220, gene) Solute carrier family 25 (mitochondrial carrier, adenine nucleotideOMIM
2(#609283, phenotype) Progressive external ophthalmoplegia with mitochondrial dna deletions,OMIM


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