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> Protein (NX_P12429)
Protein (NX_P12429)
Protein
Gene SymbolANXA3 to neXtProt (NX_P12429)
DescriptionAnnexin A3
Chromosome4
Location4q21.21 (79472673 ~ 79531597) to Ensembl
Sequene Features : Isoforms 1, Variants 60, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of sequence-specific DNA binding transcription factor activity
.positive regulation of angiogenesis
.neutrophil degranulation
  + 3 more...
.calcium-dependent protein binding
.phospholipase A2 inhibitor activity
.calcium-dependent phospholipid binding
.calcium ion binding
.extracellular exosome
.specific granule
.phagocytic vesicle membrane
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 60 2
2014-09-19protein level
1 50 2
2014-05-27protein level
1 50 2
2014-02-25protein level
1 50 2
2013-12-09protein level
1 39 2
2013-11-01protein level
1 37 1
2013-09-12protein level
1 37 1
2013-08-17protein level
1 37 1
2013-07-15protein level
1 28 1
2013-06-11protein level
1 28 1
2013-02-12protein level
1 20 1
2012-12-20protein level
1 20 1
2012-10-30protein level
1 21 1
2012-10-07protein level
1 21 1
2012-08-24protein level
1 18 1
2012-07-28protein level
1 18 1
2012-06-08protein level
1 21 1
2012-05-07protein level
1 19 1
2012-04-10protein level
1 19 1
2012-01-13protein level
1 9 1
2011-12-20protein level
1 9 1
2011-11-11protein level
1 9 1
2011-08-23protein level
1 9 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P12429-1
17 0 0 36352.5547
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
ascites50
bladder66
blood40
bone marrow246
brain9
cervix82
connective tissue20
ear124
embryonic tissue84
esophagus49
eye23
heart44
intestine64
kidney23
liver24
lung116
lymph node77
mammary gland26
muscle47
ovary88
pancreas56
pharynx98
placenta91
prostate36
salivary gland148
stomach125
testis2
thymus12
thyroid42
trachea19
umbilical cord72
uterus34
vascular38
Health State
TissuesTPM*
normal44
bladder carcinoma56
breast (mammary gland) tumor32
cervical tumor115
chondrosarcoma24
colorectal tumor26
esophageal tumor57
gastrointestinal tumor168
germ cell tumor3
glioma9
head and neck tumor22
kidney tumor29
leukemia179
liver tumor10
non-neoplasia10
ovarian tumor105
pancreatic tumor66
primitive neuroectodermal tumor of the CNS15
prostate cancer19
soft tissue/muscle tissue tumor7
uterine tumor77
Developmental Stage
TissuesTPM*
adult47
embryoid body185
neonate32
fetus25
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue37.3
adrenal gland4.2
appendix23.7
bone marrow173.2
cerebral cortex4
colon27.9
duodenum14.2
esophagus42.6
gallbladder20.4
heart muscle24.6
kidney17.6
liver2.3
lung137.9
lymph node2.3
ovary2.3
pancreas16.8
placenta62
prostate67.8
salivary gland83.4
skin3.8
small intestine11.8
spleen10.6
stomach77.8
testis1.8
thyroid gland66.4
urinary bladder10
Tissues
TissuesExpression level
adrenal glandLow
appendixMedium
bone marrowHigh
breastHigh
bronchusHigh
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1High
endometrium 2High
epididymisMedium
esophagusLow
fallopian tubeMedium
gallbladderHigh
heart muscleLow
kidneyHigh
lateral ventricleLow
liverHigh
lungHigh
lymph nodeMedium
nasopharynxHigh
oral mucosaLow
ovaryLow
pancreasHigh
parathyroid glandLow
placentaMedium
prostateHigh
rectumMedium
salivary glandMedium
seminal vesicleHigh
skeletal muscleLow
skin 1Low
skin 2Low
small intestineLow
soft tissue 1Low
soft tissue 2Medium
spleenHigh
stomach 1High
stomach 2High
testisMedium
thyroid glandHigh
tonsilMedium
urinary bladderLow
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*106490, gene) Annexin a3; ANXA3OMIM


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