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> Protein (NX_P13521)
Protein (NX_P13521)
Protein
Gene SymbolSCG2 to neXtProt (NX_P13521)
DescriptionSecretogranin-2
Chromosome2
Location2q36.1 (224461658 ~ 224467221) to Ensembl
Sequene Features : Isoforms 1, Variants 108, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of extrinsic apoptotic signaling pathway
.negative regulation of endothelial cell apoptotic process
.induction of positive chemotaxis
  + 10 more...
.chemoattractant activity
.cytokine activity
.secretory granule
.extracellular space
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 108 2
2014-09-19protein level
1 83 2
2014-05-27protein level
1 83 2
2014-02-25protein level
1 82 2
2013-12-09protein level
1 74 2
2013-11-01protein level
1 72 2
2013-09-12protein level
1 72 2
2013-08-17protein level
1 72 2
2013-07-15protein level
1 48 2
2013-06-11protein level
1 48 2
2013-02-12protein level
1 22 3
2012-12-20protein level
1 21 3
2012-10-30protein level
1 24 3
2012-10-07protein level
1 24 3
2012-08-24protein level
1 13 3
2012-07-28protein level
1 13 3
2012-06-08protein level
1 14 3
2012-05-07protein level
1 14 3
2012-04-10protein level
1 14 3
2012-01-13protein level
1 11 3
2011-12-20protein level
1 11 3
2011-11-11protein level
1 11 3
2011-08-23protein level
1 11 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P13521-1
34 0 0 70896.8402
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-947132,EBI-747353 ATRIP  
  .DNA repair
.DNA replication
.DNA damage checkpoint
.K63-linked polyubiquitin binding .nucleoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland91
bladder33
brain219
connective tissue53
embryonic tissue4
esophagus49
intestine8
kidney137
liver19
lung26
ovary9
pancreas206
pituitary gland181
placenta3
prostate5
skin9
stomach10
testis13
uterus4
vascular19
Health State
TissuesTPM*
normal76
adrenal tumor158
chondrosarcoma12
esophageal tumor57
gastrointestinal tumor8
germ cell tumor273
glioma65
kidney tumor421
liver tumor20
non-neoplasia10
pancreatic tumor66
primitive neuroectodermal tumor of the CNS149
skin tumor15
soft tissue/muscle tissue tumor47
Developmental Stage
TissuesTPM*
adult49
fetus89
infant127
juvenile197
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue7.2
adrenal gland309.3
appendix28.3
cerebral cortex126.7
colon11.3
duodenum39.6
gallbladder4.3
heart muscle1.4
ovary1.2
pancreas12.8
prostate1.8
small intestine18.7
stomach19.1
thyroid gland1.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*118930, gene) Secretogranin ii; SCG2OMIM


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