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> Protein (NX_P17022)
Protein (NX_P17022)
Protein
Gene SymbolZNF18 to neXtProt (NX_P17022)
DescriptionZinc finger protein 18
Chromosome17
Location17p12 (11880756 ~ 11900827) to Ensembl
Sequene Features : Isoforms 2, Variants 59, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.metal ion binding
.DNA binding
.sequence-specific DNA binding RNA polymerase II transcription factor activity
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 59 0
2014-09-19protein level
2 51 0
2014-05-27transcript level
2 51 0
2014-02-25transcript level
2 50 0
2013-12-09transcript level
2 37 0
2013-11-01transcript level
2 35 0
2013-09-12transcript level
2 35 0
2013-08-17transcript level
2 35 0
2013-07-15transcript level
2 25 0
2013-06-11transcript level
2 25 0
2013-02-12transcript level
2 18 0
2012-12-20transcript level
2 18 0
2012-10-30transcript level
2 23 0
2012-10-07transcript level
2 23 0
2012-08-24transcript level
2 18 0
2012-07-28transcript level
2 18 0
2012-06-08transcript level
2 18 0
2012-05-07transcript level
2 18 0
2012-04-10transcript level
2 18 0
2012-01-13transcript level
2 5 0
2011-12-20transcript level
2 5 0
2011-11-11transcript level
2 5 0
2011-08-23transcript level
2 5 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P17022-1
1 21 3 62248.447
NX_P17022-2
1 21 3 62177.4101
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-8648067,EBI-395261 CCNC  
  .positive regulation of transcription from RNA polymerase II promoter
.gene expression
.Notch signaling pathway
  + 4 more...
.N/A .mediator complex
.nucleoplasm
2 EBI-8648067,EBI-8636434 TTC32  
  .N/A .N/A .N/A
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood16
bone13
brain12
cervix20
connective tissue20
embryonic tissue4
esophagus99
eye23
heart44
intestine8
kidney14
larynx127
liver24
lung2
lymph node55
mouth15
parathyroid97
placenta7
prostate21
skin14
spleen37
stomach10
testis29
thymus12
uterus4
Health State
TissuesTPM*
normal14
cervical tumor28
chondrosarcoma12
esophageal tumor115
gastrointestinal tumor8
germ cell tumor18
glioma18
head and neck tumor29
kidney tumor14
leukemia10
liver tumor52
lymphoma13
non-neoplasia20
primitive neuroectodermal tumor of the CNS23
prostate cancer9
skin tumor15
Developmental Stage
TissuesTPM*
adult14
fetus23
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.2
adrenal gland3.9
appendix5.6
bone marrow7.2
cerebral cortex4.5
colon4.8
duodenum3.4
esophagus4.9
gallbladder5.4
heart muscle4.2
kidney4
liver3.4
lung4.2
lymph node7.3
ovary4.4
pancreas2.1
placenta3
prostate6.5
salivary gland2.4
skin6.9
small intestine4.5
spleen6.1
stomach3.8
testis11.4
thyroid gland5.2
urinary bladder4.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*194524, gene) Zinc finger protein 18; ZNF18OMIM


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