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> Protein (NX_P17024)
Protein (NX_P17024)
Protein
Gene SymbolZNF20 to neXtProt (NX_P17024)
DescriptionZinc finger protein 20
Chromosome19
Location19p13.2 (12203658 ~ 12251222) to Ensembl
Sequene Features : Isoforms 1, Variants 68, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 68 0
2014-09-19protein level
1 56 0
2014-05-27transcript level
1 56 0
2014-02-25transcript level
1 55 0
2013-12-09transcript level
1 32 0
2013-11-01transcript level
1 32 0
2013-09-12transcript level
1 32 0
2013-08-17transcript level
1 32 0
2013-07-15transcript level
1 14 0
2013-06-11transcript level
1 14 0
2013-02-12transcript level
1 7 0
2012-12-20transcript level
1 8 0
2012-10-30transcript level
1 14 0
2012-10-07transcript level
1 14 0
2012-08-24transcript level
1 10 0
2012-07-28transcript level
1 10 0
2012-06-08transcript level
1 10 0
2012-05-07transcript level
1 10 0
2012-04-10transcript level
1 10 0
2012-01-13transcript level
1 3 0
2011-12-20transcript level
1 3 0
2011-11-11transcript level
1 3 0
2011-08-23transcript level
1 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P17024-1
20 0 8 61527.1033
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-717634,EBI-5661036 FSD2  
  .N/A .N/A .N/A
2 EBI-717634,EBI-1047263 KRT38  
  .N/A .structural molecule activity .extracellular exosome
.intermediate filament
3 EBI-717634,EBI-748961 CCNDBP1  
  .regulation of cell cycle
.cell cycle
.N/A .cytoplasm
.nucleoplasm
.nucleus
4 EBI-717634,EBI-10172150 KRTAP10-5  
  .N/A .identical protein binding .keratin filament
5 EBI-717634,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
6 EBI-717634,EBI-10171774 KRTAP10-8  
  .N/A .N/A .keratin filament
7 EBI-717634,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
8 EBI-717634,EBI-359224 TRAF1  
  .regulation of extrinsic apoptotic signaling pathway
.positive regulation of NF-kappaB transcription factor activity
.signal transduction
  + 2 more...
.thioesterase binding
.ubiquitin protein ligase binding
.zinc ion binding
.tumor necrosis factor receptor binding
.cytoplasm
9 EBI-717634,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
10 EBI-717634,EBI-742948 MTUS2  
  .N/A .protein homodimerization activity
.microtubule binding
.microtubule
.cytoplasm
.nucleus
11 EBI-717634,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
12 EBI-717634,EBI-10171416 CCDC136  
  .N/A .N/A .integral component of membrane
.mitochondrion
13 EBI-717634,EBI-739863 KRTAP4-12  
  .N/A .N/A .keratin filament
14 EBI-717634,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
15 EBI-717634,EBI-2125614 KIFC3  
  .epithelial cell-cell adhesion
.zonula adherens maintenance
.metabolic process
  + 3 more...
.ATPase activity
.ATP binding
.microtubule motor activity
.extracellular exosome
.cytoplasmic vesicle membrane
.zonula adherens
  + 4 more...
16 EBI-717634,EBI-10172511 KRTAP4-2  
  .N/A .N/A .keratin filament
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites50
bladder33
blood40
bone27
brain24
connective tissue20
embryonic tissue14
intestine25
kidney18
liver4
lung11
mammary gland6
mouth15
ovary9
pancreas14
placenta3
prostate31
skin9
spleen37
testis64
thymus50
tonsil58
uterus30
Health State
TissuesTPM*
normal23
adrenal tumor79
breast (mammary gland) tumor10
chondrosarcoma12
colorectal tumor17
gastrointestinal tumor16
germ cell tumor87
head and neck tumor7
kidney tumor14
liver tumor10
lung tumor9
non-neoplasia20
primitive neuroectodermal tumor of the CNS23
prostate cancer9
uterine tumor22
Developmental Stage
TissuesTPM*
adult17
embryoid body42
neonate32
fetus28
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.6
appendix2.2
bone marrow2
cerebral cortex1.1
colon2.6
duodenum1.4
esophagus2.8
gallbladder2.2
kidney2.3
lung1.6
lymph node2.4
ovary1.9
placenta1.3
prostate2
salivary gland2.3
skin2.3
small intestine1.5
spleen1.3
stomach2.5
testis6.7
thyroid gland2.4
urinary bladder3.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*194557, gene) Zinc finger protein 20; ZNF20OMIM


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