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> Protein (NX_P17028)
Protein (NX_P17028)
Protein
Gene SymbolZNF24 to neXtProt (NX_P17028)
DescriptionZinc finger protein 24
Chromosome18
Location18q12.2 (32912176 ~ 32925446) to Ensembl
Sequene Features : Isoforms 2, Variants 40, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of transcription, DNA-templated
.myelination
.transcription, DNA-templated
.sequence-specific DNA binding
.zinc ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 40 5
2014-09-19protein level
2 39 5
2014-05-27protein level
2 39 5
2014-02-25protein level
2 39 5
2013-12-09protein level
2 35 5
2013-11-01protein level
2 34 5
2013-09-12protein level
2 34 5
2013-08-17protein level
2 34 5
2013-07-15protein level
2 21 4
2013-06-11protein level
2 21 4
2013-02-12protein level
2 7 8
2012-12-20protein level
2 7 8
2012-10-30protein level
2 11 8
2012-10-07protein level
2 11 6
2012-08-24protein level
2 9 6
2012-07-28protein level
2 9 6
2012-06-08protein level
2 3 6
2012-05-07protein level
2 3 6
2012-04-10protein level
2 3 6
2012-01-13protein level
2 3 6
2011-12-20protein level
2 5 6
2011-11-11protein level
2 5 4
2011-08-23protein level
2 5 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P17028-1
10 8 1 42128.9535
NX_P17028-2
0 8 0 22368.2401
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-707773,EBI-739696 LMO2  
  .cellular response to thyroid hormone stimulus
.positive regulation of transcription from RNA polymerase II promoter
.negative regulation of erythrocyte differentiation
  + 3 more...
.E-box binding
.cofactor binding
.bHLH transcription factor binding
  + 7 more...
.transcription factor complex
.nucleus
2 EBI-707773,EBI-351257 DDX6  
  .exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
.cytoplasmic mRNA processing body assembly
.viral RNA genome packaging
  + 4 more...
.poly(A) RNA binding
.protein domain specific binding
.ATP binding
  + 3 more...
.intracellular membrane-bounded organelle
.RISC complex
.membrane
  + 5 more...
3 EBI-707773,EBI-74648 APLP1  
  .cellular response to norepinephrine stimulus
.forebrain development
.negative regulation of cAMP biosynthetic process
  + 9 more...
.transition metal ion binding
.identical protein binding
.alpha-2C adrenergic receptor binding
  + 3 more...
.perinuclear region of cytoplasm
.integral component of membrane
.plasma membrane
  + 2 more...
4 EBI-707773,EBI-948630 DZIP3  
  .protein polyubiquitination .poly(A) RNA binding
.polyubiquitin binding
.phosphatase binding
  + 4 more...
.cytoplasm
5 EBI-707773,EBI-10290053 PGBD1  
  .N/A .scavenger receptor activity
.sequence-specific DNA binding transcription factor activity
.membrane
.nucleus
6 EBI-707773,EBI-739949 ZSCAN32  
  .transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.metal ion binding
.DNA binding
.sequence-specific DNA binding RNA polymerase II transcription factor activity
.nucleus
7 EBI-707773,EBI-10172526 MID2  
  .negative regulation of viral release from host cell
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.phosphoprotein binding
.protein heterodimerization activity
.protein homodimerization activity
  + 3 more...
.extracellular exosome
.microtubule
.cytoplasm
8 EBI-707773,EBI-750484 FAM115A  
  .positive regulation of anion channel activity
.positive regulation of protein targeting to membrane
.negative regulation of cell migration
.transport
.ion channel binding .plasma membrane
9 EBI-707773,EBI-10281938 ZSCAN21  
  .positive regulation of transcription from RNA polymerase II promoter
.regulation of transcription, DNA-templated
.metal ion binding
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II core promoter proximal region sequence-specific DNA binding
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland30
bladder100
blood57
bone41
bone marrow82
brain54
cervix41
connective tissue67
ear124
embryonic tissue75
esophagus198
eye100
heart78
intestine68
kidney47
liver53
lung53
lymph22
lymph node178
mammary gland171
mouth90
muscle122
nerve128
ovary29
pancreas131
parathyroid145
pharynx270
placenta21
prostate89
salivary gland98
skin90
stomach73
testis80
thymus50
thyroid386
tonsil117
trachea135
uterus99
vascular58
Health State
TissuesTPM*
normal81
adrenal tumor79
bladder carcinoma56
breast (mammary gland) tumor96
cervical tumor57
chondrosarcoma72
colorectal tumor106
esophageal tumor231
gastrointestinal tumor59
germ cell tumor102
glioma55
head and neck tumor194
kidney tumor58
leukemia84
liver tumor10
lung tumor19
lymphoma13
non-neoplasia41
ovarian tumor26
pancreatic tumor28
primitive neuroectodermal tumor of the CNS94
prostate cancer67
retinoblastoma129
skin tumor63
soft tissue/muscle tissue tumor63
uterine tumor122
Developmental Stage
TissuesTPM*
adult78
embryoid body100
blastocyst65
fetus89
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue16.2
adrenal gland22.2
appendix22.8
bone marrow14.4
cerebral cortex26.6
colon19.3
duodenum18.3
esophagus18.2
gallbladder19.6
heart muscle16.3
kidney21
liver14.4
lung20.9
lymph node27
ovary24.3
pancreas11.4
placenta19.9
prostate23.7
salivary gland17
skin13.3
small intestine19.1
spleen21.4
stomach20.6
testis18.6
thyroid gland32.2
urinary bladder21.2
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowHigh
breastHigh
bronchusHigh
cerebellumLow
cerebral cortexMedium
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1Medium
endometrium 2Medium
epididymisHigh
esophagusHigh
fallopian tubeHigh
gallbladderHigh
heart muscleMedium
hippocampusMedium
kidneyHigh
lateral ventricleMedium
liverLow
lungHigh
lymph nodeMedium
nasopharynxHigh
oral mucosaHigh
ovaryMedium
pancreasHigh
parathyroid glandHigh
placentaHigh
prostateHigh
rectumHigh
salivary glandHigh
seminal vesicleMedium
skeletal muscleLow
skin 1Medium
skin 2Medium
small intestineHigh
smooth muscleLow
soft tissue 1High
soft tissue 2Medium
spleenLow
stomach 1High
stomach 2High
testisMedium
thyroid glandHigh
tonsilHigh
urinary bladderHigh
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*194534, gene) Zinc finger protein 24; ZNF24OMIM


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