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> Protein (NX_P17509)
Protein (NX_P17509)
Protein
Gene SymbolHOXB6 to neXtProt (NX_P17509)
DescriptionHomeobox protein Hox-B6
Chromosome17
Location17q21.32 (46671639 ~ 46682354) to Ensembl
Sequene Features : Isoforms 2, Variants 21, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.embryonic skeletal system morphogenesis
.erythrocyte homeostasis
.anterior/posterior pattern specification
.transcription, DNA-templated
.poly(A) RNA binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 21 1
2014-09-19protein level
2 15 1
2014-05-27protein level
2 15 1
2014-02-25protein level
2 15 1
2013-12-09protein level
2 12 1
2013-11-01protein level
2 12 1
2013-09-12protein level
2 12 1
2013-08-17protein level
2 12 1
2013-07-15protein level
2 8 1
2013-06-11protein level
2 8 1
2013-02-12protein level
2 5 2
2012-12-20protein level
2 4 2
2012-10-30protein level
2 5 2
2012-10-07protein level
2 5 2
2012-08-24protein level
2 3 2
2012-07-28protein level
2 3 2
2012-06-08protein level
2 5 2
2012-05-07protein level
2 5 2
2012-04-10protein level
2 5 2
2012-01-13protein level
2 5 2
2011-12-20protein level
2 5 2
2011-11-11protein level
2 5 2
2011-08-23protein level
2 5 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P17509-1
2 7 2 25416.1485
NX_P17509-2
0 7 0 15161.8361
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-741308,EBI-745579 CLK3  
  .protein autophosphorylation
.regulation of RNA splicing
.protein phosphorylation
.poly(A) RNA binding
.ATP binding
.protein tyrosine kinase activity
  + 2 more...
.intermediate filament cytoskeleton
.nuclear speck
.membrane
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
bone13
cervix20
connective tissue13
embryonic tissue18
intestine86
kidney28
liver4
lung8
mammary gland6
nerve64
ovary9
pancreas18
placenta3
prostate21
spleen18
testis11
uterus21
Health State
TissuesTPM*
normal7
breast (mammary gland) tumor10
chondrosarcoma48
colorectal tumor88
gastrointestinal tumor25
germ cell tumor15
kidney tumor14
leukemia31
lung tumor9
pancreatic tumor38
uterine tumor44
Developmental Stage
TissuesTPM*
adult11
embryoid body57
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4
adrenal gland4.6
appendix5.1
colon8.5
duodenum1.2
kidney16.8
lung2.9
placenta2.2
small intestine4.4
spleen1.1
stomach1.6
testis1.1
urinary bladder7.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*142961, gene) Homeobox b6; HOXB6OMIM


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