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> Protein (NX_P17544)
Protein (NX_P17544)
Protein
Gene SymbolATF7 to neXtProt (NX_P17544)
DescriptionCyclic AMP-dependent transcription factor ATF-7
Chromosome12
Location12q13.13 (53901640 ~ 54020199) to Ensembl
Sequene Features : Isoforms 6, Variants 34, PTMs 13 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.viral process
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.negative regulation of transcription from RNA polymerase II promoter
.mitogen-activated protein kinase binding
.metal ion binding
.sequence-specific DNA binding
  + 5 more...
.nuclear periphery
.cytoplasm
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
6 34 13
2014-09-19protein level
6 23 13
2014-05-27protein level
6 23 14
2014-02-25protein level
6 22 14
2013-12-09protein level
6 16 14
2013-11-01protein level
6 16 13
2013-09-12protein level
6 16 13
2013-08-17protein level
6 16 13
2013-07-15protein level
6 8 13
2013-06-11protein level
6 8 13
2013-02-12protein level
6 3 81
2012-12-20protein level
6 2 81
2012-10-30protein level
6 4 81
2012-10-07protein level
6 4 18
2012-08-24protein level
6 2 18
2012-07-28protein level
6 2 18
2012-06-08protein level
6 17 18
2012-05-07protein level
6 17 18
2012-04-10protein level
5 17 18
2012-01-13protein level
4 16 18
2011-12-20protein level
4 16 18
2011-11-11protein level
4 16 17
2011-08-23protein level
4 16 17
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P17544-1
0 16 1 52933.9871
NX_P17544-2
0 15 1 49618.236
NX_P17544-3
0 15 1 50827.9989
NX_P17544-4
1 13 1 33659.842
NX_P17544-5
1 3 1 13269.7593
NX_P17544-6
0 16 1 51724.2242
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-765623,EBI-10199985 FCER2  
  .positive regulation of nitric-oxide synthase biosynthetic process
.positive regulation of killing of cells of other organism
.positive regulation of nitric-oxide synthase activity
  + 2 more...
.metal ion binding
.carbohydrate binding
.integrin binding
.extracellular exosome
.external side of plasma membrane
.integral component of plasma membrane
.plasma membrane
2 EBI-765623,EBI-10175124 FAM9B  
  .spermatid development .N/A .nucleoplasm
3 EBI-765623,EBI-749265 CCDC155  
  .chromosome localization to nuclear envelope involved in homologous chromosome segregation
.oogenesis
.spermatogenesis
  + 2 more...
.N/A .integral component of membrane
.nuclear outer membrane
.lateral element
.chromosome, telomeric region
4 EBI-765623,EBI-9675724 TMEM239  
  .N/A .N/A .integral component of membrane
5 EBI-765623,EBI-2683029 OCIAD1  
  .N/A .N/A .membrane
.endosome
.mitochondrion
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites25
bladder33
blood8
bone27
bone marrow41
brain45
connective tissue20
embryonic tissue14
eye19
heart11
intestine34
kidney23
larynx127
liver19
lung2
lymph node44
mammary gland46
mouth45
muscle37
ovary19
pancreas4
pharynx49
placenta10
prostate26
salivary gland49
skin14
stomach10
testis45
thyroid42
trachea38
uterus12
vascular19
Health State
TissuesTPM*
normal25
adrenal tumor79
breast (mammary gland) tumor10
chondrosarcoma12
colorectal tumor53
gastrointestinal tumor8
germ cell tumor22
glioma65
head and neck tumor59
kidney tumor29
leukemia10
liver tumor10
lung tumor9
non-neoplasia20
ovarian tumor13
prostate cancer28
soft tissue/muscle tissue tumor23
uterine tumor11
Developmental Stage
TissuesTPM*
adult5
embryoid body14
blastocyst16
fetus1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue21.9
adrenal gland13.5
appendix17.2
bone marrow9.5
cerebral cortex12.2
colon17.2
duodenum9.7
esophagus27.1
gallbladder22.1
heart muscle15.8
kidney14.5
liver8.2
lung18.3
lymph node13.8
ovary23.9
pancreas9
placenta17
prostate18.9
salivary gland16.5
skin19.4
small intestine11.3
spleen14.4
stomach13.6
testis14.5
thyroid gland19.8
urinary bladder25.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*606371, gene) Activating transcription factor 7; ATF7OMIM


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