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> Protein (NX_P18669)
Protein (NX_P18669)
Protein
Gene SymbolPGAM1 to neXtProt (NX_P18669)
DescriptionPhosphoglycerate mutase 1
Chromosome10
Location10q24.1 (99185917 ~ 99193198) to Ensembl
Sequene Features : Isoforms 1, Variants 19, PTMs 15 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.canonical glycolysis
.respiratory burst
.small molecule metabolic process
  + 6 more...
.protein kinase binding
.phosphoglycerate mutase activity
.bisphosphoglycerate 2-phosphatase activity
.bisphosphoglycerate mutase activity
.extracellular exosome
.membrane
.cytosol
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 19 15
2014-09-19protein level
1 18 15
2014-05-27protein level
1 18 25
2014-02-25protein level
1 18 23
2013-12-09protein level
1 12 23
2013-11-01protein level
1 12 18
2013-09-12protein level
1 12 18
2013-08-17protein level
1 12 18
2013-07-15protein level
1 7 12
2013-06-11protein level
1 7 12
2013-02-12protein level
1 4 12
2012-12-20protein level
1 4 12
2012-10-30protein level
1 5 12
2012-10-07protein level
1 5 12
2012-08-24protein level
1 5 12
2012-07-28protein level
1 5 12
2012-06-08protein level
1 5 9
2012-05-07protein level
1 5 9
2012-04-10protein level
1 5 9
2012-01-13protein level
1 6 9
2011-12-20protein level
1 6 9
2011-11-11protein level
1 6 8
2011-08-23protein level
1 6 6
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P18669-1
6 0 6 28785.7525
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-717905,EBI-358311 PCNA  
  .error-free translesion synthesis
.response to cadmium ion
.positive regulation of DNA replication
  + 24 more...
.DNA polymerase binding
.identical protein binding
.histone acetyltransferase binding
  + 7 more...
.PCNA-p21 complex
.extracellular exosome
.PCNA complex
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland728
ascites326
bladder234
blood1096
bone363
bone marrow143
brain417
cervix907
connective tissue248
ear372
embryonic tissue831
esophagus1339
eye588
heart301
intestine456
kidney426
larynx383
liver160
lung385
lymph1602
lymph node189
mammary gland264
mouth468
muscle216
nerve193
ovary620
pancreas463
parathyroid776
pharynx122
pituitary gland242
placenta628
prostate517
salivary gland1529
skin512
spleen280
stomach428
testis160
thymus87
thyroid300
tonsil822
umbilical cord799
uterus473
vascular116
Health State
TissuesTPM*
normal301
adrenal tumor790
bladder carcinoma113
breast (mammary gland) tumor290
cervical tumor1043
chondrosarcoma386
colorectal tumor364
esophageal tumor927
gastrointestinal tumor464
germ cell tumor668
glioma541
head and neck tumor642
kidney tumor842
leukemia1344
liver tumor270
lung tumor622
lymphoma1232
non-neoplasia796
ovarian tumor406
pancreatic tumor761
primitive neuroectodermal tumor of the CNS716
prostate cancer751
retinoblastoma602
skin tumor542
soft tissue/muscle tissue tumor471
uterine tumor543
Developmental Stage
TissuesTPM*
adult407
embryoid body700
blastocyst895
neonate450
fetus210
infant978
juvenile575
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue61.2
adrenal gland97.8
appendix77.3
bone marrow54.2
cerebral cortex116.7
colon74.6
duodenum68.2
esophagus145.3
gallbladder60.5
heart muscle105.4
kidney73.5
liver42.3
lung49.4
lymph node82
ovary50.1
pancreas16.3
placenta72.4
prostate51.2
salivary gland40.8
skin69.6
small intestine65.5
spleen48.7
stomach41.4
testis53.6
thyroid gland45.3
urinary bladder90.1
Tissues
TissuesExpression level
adrenal glandMedium
appendixLow
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonLow
endometrium 1Low
epididymisMedium
esophagusLow
fallopian tubeLow
gallbladderLow
heart muscleLow
hippocampusMedium
kidneyHigh
lateral ventricleLow
liverLow
lungLow
lymph nodeLow
nasopharynxLow
oral mucosaLow
ovaryLow
pancreasMedium
parathyroid glandLow
placentaLow
prostateLow
rectumMedium
salivary glandLow
seminal vesicleMedium
skin 1Low
skin 2Medium
small intestineLow
smooth muscleLow
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandMedium
tonsilMedium
urinary bladderMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*172250, gene) Phosphoglycerate mutase 1; PGAM1OMIM


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