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> Protein (NX_P18825)
Protein (NX_P18825)
Protein
Gene SymbolADRA2C to neXtProt (NX_P18825)
DescriptionAlpha-2C adrenergic receptor
Chromosome4
Location4p16.3 (3768075 ~ 3770251) to Ensembl
Sequene Features : Isoforms 1, Variants 34, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.activation of MAPK activity by adrenergic receptor signaling pathway
.adenylate cyclase-inhibiting adrenergic receptor signaling pathway
.negative regulation of uterine smooth muscle contraction
  + 18 more...
.epinephrine binding
.protein heterodimerization activity
.protein homodimerization activity
  + 2 more...
.axon terminus
.integral component of plasma membrane
.plasma membrane
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
1 34 3
2014-09-19transcript level
1 22 3
2014-05-27protein level
1 22 3
2014-02-25protein level
1 22 3
2013-12-09protein level
1 19 3
2013-11-01protein level
1 18 3
2013-09-12protein level
1 18 3
2013-08-17protein level
1 18 3
2013-07-15protein level
1 12 3
2013-06-11protein level
1 12 3
2013-02-12transcript level
1 3 3
2012-12-20transcript level
1 3 3
2012-10-30transcript level
1 3 3
2012-10-07transcript level
1 3 3
2012-08-24transcript level
1 3 3
2012-07-28transcript level
1 3 3
2012-06-08transcript level
1 7 3
2012-05-07transcript level
1 7 3
2012-04-10transcript level
1 7 3
2012-01-13transcript level
1 11 3
2011-12-20transcript level
1 11 3
2011-11-11transcript level
1 11 3
2011-08-23transcript level
1 11 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P18825-1
13 0 0 49490.5738
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
connective tissue6
embryonic tissue9
heart11
kidney9
mammary gland19
ovary9
pancreas9
placenta21
testis2
trachea19
uterus17
Health State
TissuesTPM*
normal4
breast (mammary gland) tumor32
glioma9
kidney tumor14
ovarian tumor13
pancreatic tumor9
primitive neuroectodermal tumor of the CNS7
uterine tumor33
Developmental Stage
TissuesTPM*
adult6
embryoid body14
fetus3
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.8
adrenal gland1.2
cerebral cortex1.4
kidney5.9
pancreas1.4
placenta3.2
prostate2.7
spleen4.8
testis1.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(+104250, gene/phenotype) Alpha-2c-adrenergic receptor; ADRA2COMIM


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