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> Protein (NX_P19105)
Protein (NX_P19105)
Protein
Gene SymbolMYL12A to neXtProt (NX_P19105)
DescriptionMyosin regulatory light chain 12A
Chromosome18
Location18p11.31 (3247479 ~ 3256234) to Ensembl
Sequene Features : Isoforms 1, Variants 15, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein targeting to plasma membrane
.platelet aggregation
.ephrin receptor signaling pathway
  + 3 more...
.calcium ion binding .extracellular exosome
.Z disc
.myosin II complex
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 15 2
2014-09-19protein level
1 12 2
2014-05-27protein level
1 12 5
2014-02-25protein level
1 12 5
2013-12-09protein level
1 6 5
2013-11-01protein level
1 6 4
2013-09-12protein level
1 6 4
2013-08-17protein level
1 6 4
2013-07-15protein level
1 1 4
2013-06-11protein level
1 1 4
2013-02-12protein level
1 0 6
2012-12-20protein level
1 0 6
2012-10-30protein level
1 1 6
2012-10-07protein level
1 1 6
2012-08-24protein level
1 1 6
2012-07-28protein level
1 1 6
2012-06-08protein level
1 1 6
2012-05-07protein level
1 1 6
2012-04-10protein level
1 1 6
2012-01-13protein level
1 4 6
2011-12-20protein level
1 4 6
2011-11-11protein level
1 4 6
2011-08-23protein level
1 4 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P19105-1
1 0 8 19781.4359
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland273
ascites301
bladder669
blood441
bone684
bone marrow451
brain52
cervix82
connective tissue228
ear372
embryonic tissue310
esophagus49
eye253
heart524
intestine297
kidney180
larynx213
liver306
lung887
lymph67
lymph node122
mammary gland1401
mouth75
muscle1588
nerve386
ovary157
pancreas580
parathyroid242
pharynx1080
pituitary gland60
placenta113
prostate189
salivary gland197
skin256
spleen37
stomach344
testis78
thymus50
thyroid880
tonsil117
umbilical cord653
uterus685
vascular387
Health State
TissuesTPM*
normal307
adrenal tumor553
bladder carcinoma1194
breast (mammary gland) tumor805
cervical tumor115
chondrosarcoma627
colorectal tumor151
esophageal tumor57
gastrointestinal tumor286
germ cell tumor91
glioma130
head and neck tumor381
kidney tumor261
leukemia433
liver tumor249
lung tumor2111
lymphoma221
non-neoplasia93
ovarian tumor170
pancreatic tumor447
primitive neuroectodermal tumor of the CNS62
prostate cancer182
retinoblastoma129
skin tumor175
soft tissue/muscle tissue tumor199
uterine tumor1409
Developmental Stage
TissuesTPM*
adult533
embryoid body514
blastocyst195
neonate289
fetus152
infant42
juvenile107
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue276.3
adrenal gland211.9
appendix309.2
bone marrow245.4
cerebral cortex32.6
colon314.2
duodenum233.7
esophagus328.6
gallbladder318.4
heart muscle2038.7
kidney217.1
liver186.5
lung403.5
lymph node429.9
ovary144.9
pancreas79.9
placenta298.4
prostate212.4
salivary gland118.5
skin142.3
small intestine249.3
spleen379.1
stomach260.2
testis98.5
thyroid gland251.7
urinary bladder323.7
Tissues
TissuesExpression level
breastMedium
cerebral cortexLow
colonLow
heart muscleMedium
kidneyLow
placentaLow
skeletal muscleMedium
smooth muscleHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*609211, gene) Myosin, light chain 12b, regulatory; MYL12BOMIM


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