Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_P21757)
Protein (NX_P21757)
Protein
Gene SymbolMSR1 to neXtProt (NX_P21757)
DescriptionMacrophage scavenger receptor types I and II
Chromosome8
Location8p22 (15965387 ~ 16424999) to Ensembl
Sequene Features : Isoforms 3, Variants 149, PTMs 11 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to organic cyclic compound
.lipoprotein transport
.plasma lipoprotein particle clearance
  + 4 more...
.low-density lipoprotein particle binding
.scavenger receptor activity
.low-density lipoprotein particle
.endocytic vesicle membrane
.integral component of plasma membrane
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 149 11
2014-09-19protein level
3 93 11
2014-05-27protein level
3 93 11
2014-02-25protein level
3 92 11
2013-12-09protein level
3 73 11
2013-11-01protein level
3 64 11
2013-09-12protein level
3 64 12
2013-08-17protein level
3 64 12
2013-07-15protein level
3 51 12
2013-06-11protein level
3 51 12
2013-02-12protein level
3 26 31
2012-12-20protein level
3 27 31
2012-10-30protein level
3 29 31
2012-10-07protein level
3 29 12
2012-08-24protein level
3 25 12
2012-07-28protein level
3 25 12
2012-06-08protein level
3 25 12
2012-05-07protein level
3 25 12
2012-04-10protein level
3 25 12
2012-01-13protein level
3 16 12
2011-12-20protein level
3 16 12
2011-11-11protein level
3 11 12
2011-08-23protein level
3 11 12
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P21757-1
5 21 0 49730.6783
NX_P21757-2
1 19 0 39558.809
NX_P21757-3
1 21 0 42915.225
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1776976,EBI-721179 ATP6V0C  
  .phagosome maturation
.transmembrane transport
.interaction with host
  + 8 more...
.proton-transporting ATPase activity, rotational mechanism
.proton-transporting ATP synthase activity, rotational mechanism
.ubiquitin protein ligase binding
.extracellular exosome
.proton-transporting V-type ATPase, V0 domain
.phagocytic vesicle membrane
  + 4 more...
2 EBI-1776976,EBI-750078 MALL  
  .cholesterol homeostasis .N/A .membrane raft
.clathrin-coated vesicle
.cytoplasmic membrane-bounded vesicle
  + 3 more...
3 EBI-1776976,EBI-3919611 NKG7  
  .N/A .N/A .integral component of plasma membrane
4 EBI-1776976,EBI-1777078 HOOK3  
  .neuronal stem cell maintenance
.protein localization to centrosome
.Golgi localization
  + 9 more...
.identical protein binding
.microtubule binding
.FHF complex
.centriolar satellite
.microtubule
  + 6 more...
5 EBI-1776976,EBI-8652744 SEC22A  
  .vesicle fusion with Golgi apparatus
.protein transport
.ER to Golgi vesicle-mediated transport
.SNAP receptor activity
.transporter activity
.SNARE binding
.SNARE complex
.integral component of membrane
.endoplasmic reticulum membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
bladder33
blood40
brain1
connective tissue87
heart11
intestine21
kidney28
larynx42
liver4
lung41
mammary gland26
pancreas18
pharynx24
placenta21
spleen37
testis2
trachea19
uterus4
vascular38
Health State
TissuesTPM*
normal8
adrenal tumor79
breast (mammary gland) tumor42
colorectal tumor35
head and neck tumor7
kidney tumor14
non-neoplasia144
pancreatic tumor9
Developmental Stage
TissuesTPM*
adult17
fetus5
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue23.1
adrenal gland19.9
appendix18.2
cerebral cortex8.7
colon8.7
duodenum5.4
esophagus6
gallbladder31.7
heart muscle5.7
kidney6.5
liver12.2
lung78.6
lymph node6.5
ovary5.2
pancreas3.3
placenta22.5
prostate2.5
salivary gland3.1
small intestine7.7
spleen14.5
stomach6.9
testis6.9
thyroid gland5
urinary bladder18.8
Tissues
TissuesExpression level
bone marrowMedium
lungHigh
ovaryMedium
spleenMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*153622, gene) Macrophage scavenger receptor; MSR1OMIM
2(#176807, phenotype) Prostate cancerOMIM
3(#614266, phenotype) Barrett esophagusOMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2020 (C) Yonsei Proteome Research Center