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> Protein (NX_P21918)
Protein (NX_P21918)
Protein
Gene SymbolDRD5 to neXtProt (NX_P21918)
DescriptionD(1B) dopamine receptor
Chromosome4
Location4p16.1 (9783258 ~ 9785632) to Ensembl
Sequene Features : Isoforms 1, Variants 136, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.reactive oxygen species metabolic process
.cellular response to catecholamine stimulus
.long term synaptic depression
  + 22 more...
.dopamine binding
.G-protein coupled amine receptor activity
.dopamine neurotransmitter receptor activity
.dopamine neurotransmitter receptor activity, coupled via Gs
.brush border membrane
.integral component of plasma membrane
.plasma membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 136 4
2014-09-19protein level
1 95 4
2014-05-27protein level
1 95 4
2014-02-25protein level
1 95 4
2013-12-09protein level
1 87 4
2013-11-01protein level
1 85 4
2013-09-12protein level
1 85 4
2013-08-17protein level
1 85 4
2013-07-15protein level
1 59 4
2013-06-11protein level
1 59 4
2013-02-12protein level
1 36 4
2012-12-20protein level
1 36 4
2012-10-30protein level
1 33 4
2012-10-07protein level
1 33 4
2012-08-24protein level
1 28 4
2012-07-28protein level
1 28 4
2012-06-08protein level
1 29 4
2012-05-07protein level
1 24 4
2012-04-10protein level
1 24 4
2012-01-13protein level
1 20 4
2011-12-20protein level
1 20 4
2011-11-11protein level
1 20 4
2011-08-23protein level
1 20 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P21918-1
16 0 0 52916.2023
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain3
eye19
ovary19
Health State
TissuesTPM*
normal2
ovarian tumor26
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
appendix1.2
cerebral cortex1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(+126453, gene/phenotype) Dopamine receptor d5; DRD5OMIM
2(#606798, phenotype) Blepharospasm, benign essentialOMIM


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