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> Protein (NX_P22466)
Protein (NX_P22466)
Protein
Gene SymbolGAL to neXtProt (NX_P22466)
DescriptionGalanin peptides
Chromosome11
Location11q13.3 (68451247 ~ 68458643) to Ensembl
Sequene Features : Isoforms 1, Variants 20, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of root hair elongation
.positive regulation of large conductance calcium-activated potassium channel activity
.positive regulation of catagen
  + 16 more...
.type 3 galanin receptor binding
.type 2 galanin receptor binding
.type 1 galanin receptor binding
.neuropeptide hormone activity
.neuronal cell body
.secretory granule
.Golgi apparatus
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 20 4
2014-09-19protein level
1 19 4
2014-05-27protein level
1 19 4
2014-02-25protein level
1 19 4
2013-12-09protein level
1 13 4
2013-11-01protein level
1 13 4
2013-09-12protein level
1 13 4
2013-08-17protein level
1 13 4
2013-07-15protein level
1 9 3
2013-06-11protein level
1 9 3
2013-02-12protein level
1 4 2
2012-12-20protein level
1 4 2
2012-10-30protein level
1 4 2
2012-10-07protein level
1 4 2
2012-08-24protein level
1 4 2
2012-07-28protein level
1 4 2
2012-06-08protein level
1 4 2
2012-05-07protein level
1 4 2
2012-04-10protein level
1 4 2
2012-01-13protein level
1 2 2
2011-12-20protein level
1 2 2
2011-11-11protein level
1 2 2
2011-08-23protein level
1 2 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P22466-1
6 0 0 13293.8865
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-6624800,EBI-6624855 GALR2  
  .positive regulation of large conductance calcium-activated potassium channel activity
.positive regulation of transcription from RNA polymerase II promoter
.neuron projection development
  + 11 more...
.peptide hormone binding
.galanin receptor activity
.integral component of membrane
.plasma membrane
2 EBI-6624768,EBI-347996 SGTA  
  .viral process .N/A .cytoplasm
3 EBI-6624800,EBI-6624741 GALR1  
  .positive regulation of cortisol secretion
.positive regulation of transcription from RNA polymerase II promoter
.digestion
  + 4 more...
.neuropeptide binding
.peptide hormone binding
.galanin receptor activity
.integral component of membrane
.plasma membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites100
blood8
bone13
cervix61
connective tissue20
embryonic tissue46
intestine4
lung5
lymph node11
nerve64
ovary9
pancreas14
pituitary gland1815
prostate10
stomach10
Health State
TissuesTPM*
normal13
cervical tumor28
chondrosarcoma12
gastrointestinal tumor42
germ cell tumor49
leukemia21
lung tumor9
pancreatic tumor19
primitive neuroectodermal tumor of the CNS7
prostate cancer9
soft tissue/muscle tissue tumor23
Developmental Stage
TissuesTPM*
adult22
blastocyst32
fetus1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.7
appendix11
cerebral cortex1.5
colon5
skin1.1
small intestine1.7
Tissues
TissuesExpression level
adrenal glandLow
appendixLow
colonHigh
duodenumLow
liverLow
parathyroid glandLow
skeletal muscleLow
small intestineLow
testisLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*137035, gene) Galanin; GALOMIM


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