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> Protein (NX_P23763)
Protein (NX_P23763)
Protein
Gene SymbolVAMP1 to neXtProt (NX_P23763)
DescriptionVesicle-associated membrane protein 1
Chromosome12
Location12p13.31 (6571403 ~ 6580153) to Ensembl
Sequene Features : Isoforms 3, Variants 6, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.SNARE complex assembly
.vesicle fusion
.exocytosis
.SNAP receptor activity
.SNARE binding
.tertiary granule membrane
.neuron projection
.specific granule membrane
  + 8 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 6 0
2014-09-19protein level
3 5 0
2014-05-27protein level
3 5 2
2014-02-25protein level
3 5 2
2013-12-09protein level
3 3 2
2013-11-01protein level
3 3 2
2013-09-12protein level
3 3 2
2013-08-17protein level
3 3 2
2013-07-15protein level
3 1 2
2013-06-11protein level
3 1 2
2013-02-12protein level
3 1 6
2012-12-20protein level
3 2 6
2012-10-30protein level
3 2 6
2012-10-07protein level
3 2 2
2012-08-24protein level
3 1 2
2012-07-28protein level
3 1 2
2012-06-08protein level
3 2 2
2012-05-07protein level
3 2 2
2012-04-10protein level
3 2 2
2012-01-13protein level
3 3 2
2011-12-20protein level
3 3 2
2011-11-11protein level
3 3 2
2011-08-23protein level
3 3 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P23763-1
1 3 0 12893.5613
NX_P23763-2
1 3 0 12649.4587
NX_P23763-3
1 3 0 12756.5208
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10201335,EBI-490676 SNAP29  
  .membrane fusion
.synaptic vesicle fusion to presynaptic membrane
.synaptic vesicle priming
  + 4 more...
.syntaxin binding
.SNAP receptor activity
.synapse
.neuron projection
.SNARE complex
  + 4 more...
2 EBI-10201335,EBI-744942 STX4  
  .positive regulation of protein localization to cell surface
.positive regulation of protein localization to plasma membrane
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
  + 21 more...
.sphingomyelin phosphodiesterase activator activity
.SNAP receptor activity
.SNARE binding
.extracellular exosome
.perinuclear region of cytoplasm
.synapse
  + 19 more...
3 EBI-10201335,EBI-749265 CCDC155  
  .chromosome localization to nuclear envelope involved in homologous chromosome segregation
.oogenesis
.spermatogenesis
  + 2 more...
.N/A .integral component of membrane
.nuclear outer membrane
.lateral element
.chromosome, telomeric region
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites50
bladder33
blood122
bone41
brain171
connective tissue67
embryonic tissue14
eye43
heart89
intestine25
kidney118
larynx85
lung14
lymph node178
mammary gland13
mouth45
nerve257
ovary9
prostate26
skin23
spleen243
stomach31
testis45
thymus1129
thyroid42
tonsil58
trachea19
uterus25
Health State
TissuesTPM*
normal85
adrenal tumor79
breast (mammary gland) tumor21
chondrosarcoma12
colorectal tumor26
gastrointestinal tumor16
germ cell tumor75
glioma55
head and neck tumor44
kidney tumor348
leukemia232
lung tumor9
lymphoma13
non-neoplasia155
ovarian tumor13
skin tumor31
uterine tumor22
Developmental Stage
TissuesTPM*
adult48
blastocyst32
fetus50
juvenile89
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.3
adrenal gland9.3
appendix20.3
bone marrow39.9
cerebral cortex24.2
colon5.2
duodenum7.5
esophagus5.5
gallbladder7.4
heart muscle4.5
kidney4.5
liver3.5
lung8.4
lymph node34.7
ovary4.9
pancreas1.9
placenta2.6
prostate11.9
salivary gland7
skin4.9
small intestine7.8
spleen18.3
stomach7.1
testis6.6
thyroid gland10.5
urinary bladder9.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(%108600, phenotype) Spastic ataxia 1, autosomal dominant; SPAX1OMIM
2(*185880, gene) Vesicle-associated membrane protein 1; VAMP1OMIM


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