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> Protein (NX_P26641)
Protein (NX_P26641)
Protein
Gene SymbolEEF1G to neXtProt (NX_P26641)
DescriptionElongation factor 1-gamma
Chromosome11
Location11q12.3 (62327073 ~ 62342401) to Ensembl
Sequene Features : Isoforms 2, Variants 36, PTMs 15 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular protein metabolic process
.gene expression
.response to virus
  + 2 more...
.translation elongation factor activity .extracellular exosome
.membrane
.cytosol
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 36 15
2014-09-19protein level
1 26 15
2014-05-27protein level
1 26 16
2014-02-25protein level
1 26 15
2013-12-09protein level
1 21 15
2013-11-01protein level
1 20 11
2013-09-12protein level
1 20 11
2013-08-17protein level
1 20 11
2013-07-15protein level
1 15 7
2013-06-11protein level
1 15 7
2013-02-12protein level
1 5 10
2012-12-20protein level
1 5 10
2012-10-30protein level
1 6 10
2012-10-07protein level
1 6 10
2012-08-24protein level
1 3 10
2012-07-28protein level
1 3 10
2012-06-08protein level
1 4 10
2012-05-07protein level
1 4 10
2012-04-10protein level
1 4 10
2012-01-13protein level
1 12 9
2011-12-20protein level
1 12 9
2011-11-11protein level
1 9 7
2011-08-23protein level
1 9 6
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P26641-1
1 19 0 50087.0026
NX_P26641-2
4 19 0 56114.2012
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10177695,EBI-2510096 KLHL18  
  .N/A .N/A .N/A
2 EBI-351467,EBI-354334 EEF1B2  
  .cellular protein metabolic process
.gene expression
.translational elongation
.translation
.translation elongation factor activity .eukaryotic translation elongation factor 1 complex
.cytosol
.cytoplasm
3 EBI-351467,EBI-358607 EEF1D  
  .cellular response to ionizing radiation
.cellular protein metabolic process
.positive regulation of I-kappaB kinase/NF-kappaB signaling
  + 8 more...
.activating transcription factor binding
.heat shock protein binding
.translation factor activity, RNA binding
  + 3 more...
.eukaryotic translation elongation factor 1 complex
.cytosol
.cytoplasm
  + 2 more...
4 EBI-10177695,EBI-2692323 RBM6  
  .RNA processing .poly(A) RNA binding
.RNA binding
.DNA binding
.nucleotide binding
.nucleus
5 EBI-10177695,EBI-10248874 EEF1DP3  
  .N/A .translation elongation factor activity .N/A
6 EBI-351467,EBI-5661333 TRIM63  
  .cellular response to dexamethasone stimulus
.response to interleukin-1
.proteasome-mediated ubiquitin-dependent protein catabolic process
  + 5 more...
.titin binding
.ligase activity
.zinc ion binding
  + 2 more...
.M band
.Z disc
.microtubule
  + 2 more...
7 EBI-10177695,EBI-714824 PLGRKT  
  .positive regulation of plasminogen activation
.inflammatory response
.chemotaxis
.N/A .integral component of plasma membrane
.mitochondrion
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue1554
adrenal gland637
ascites1832
bladder971
blood1169
bone740
bone marrow1703
brain927
cervix6166
connective tissue415
ear248
embryonic tissue3292
esophagus1885
eye2858
heart927
intestine2776
kidney1342
larynx1278
liver2615
lung1633
lymph7448
lymph node1593
mammary gland1276
mouth302
muscle3525
nerve1738
ovary2167
pancreas1681
parathyroid485
pharynx5672
pituitary gland968
placenta703
prostate1799
salivary gland3700
skin1632
spleen1404
stomach2111
testis551
thymus765
thyroid837
tonsil5640
umbilical cord1598
uterus1938
vascular677
Health State
TissuesTPM*
normal234
adrenal tumor1185
bladder carcinoma853
breast (mammary gland) tumor1955
cervical tumor8554
chondrosarcoma422
colorectal tumor4106
esophageal tumor2029
gastrointestinal tumor2523
germ cell tumor2283
glioma2546
head and neck tumor1001
kidney tumor2628
leukemia1238
liver tumor4373
lung tumor4271
lymphoma5221
non-neoplasia424
ovarian tumor1811
pancreatic tumor2218
primitive neuroectodermal tumor of the CNS2850
prostate cancer2802
retinoblastoma8484
skin tumor2057
soft tissue/muscle tissue tumor3384
uterine tumor2008
Developmental Stage
TissuesTPM*
adult1000
embryoid body2929
blastocyst3433
neonate740
fetus631
infant5529
juvenile1619
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue125.7
adrenal gland115.1
appendix153.5
bone marrow153.3
cerebral cortex54.5
colon212.6
duodenum149.3
esophagus188.2
gallbladder112.5
heart muscle115.3
kidney140.2
liver79.5
lung106.3
lymph node202.1
ovary322.5
pancreas145.7
placenta108.1
prostate165.3
salivary gland167.3
skin202.1
small intestine149.8
spleen137.7
stomach143.5
testis62.4
thyroid gland145.6
urinary bladder165.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*130593, gene) Eukaryotic translation elongation factor 1, gamma; EEF1GOMIM


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